The failure of chromosome 21 to segregate during egg or sperm development produces a gamete with 24 chromosomes. This mutated gamete, when fused with a normal gamete, results in a fetus with an extra copy of chromosome 21. Which type of mutation during cell division is responsible for the occurrence of this disorder? deletion

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The failure of chromosome 21 to segregate during egg or sperm development produces a
gamete with 24 chromosomes. This mutated gamete, when fused with a normal gamete, results
in a fetus with an extra copy of chromosome 21.
Which type of mutation during cell division is responsible for the occurrence of this disorder?
deletion
O nondisjunction
substitution
O translocation
Transcribed Image Text:The failure of chromosome 21 to segregate during egg or sperm development produces a gamete with 24 chromosomes. This mutated gamete, when fused with a normal gamete, results in a fetus with an extra copy of chromosome 21. Which type of mutation during cell division is responsible for the occurrence of this disorder? deletion O nondisjunction substitution O translocation
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