Like whippets, Thoroughbred horses have been intensely bred and selected primarily for speed by humans. Unlike whippets, Thoroughbred horses race shorter or longer races. The ability to successfully race a long distance is called "distance aptitude". Short races that have increased in popularity since the 19th century favor sprinters. A GWAS study found a g.66493737C>T SNP association with distance aptitude that had a p value of 1.02 x 10-10. In other words, the presence of a T SNP, rather than a C SNP, is associated with distance aptitude with a p value of 1.02 x 10-10. On average the optimum racing distance for C:C horses was 6.2 ± 0.8 furlongs, for C:T horses was 9.1 ± 2.4 furlongs and for T:T horses was 10.5 ± 2.7 furlongs. Furthermore, C:C horses have significantly greater muscle mass than T:T horses at two-years-old, indicating that the C SNP negatively affects myostatin. Which statement is correct regarding whether the g.66493737C>T SNP association with distance aptitude is significant or not in terms of the exact probability that the T:T SNP is associated with distance aptitude by coincidence, or random chance. Keep in mind that a p value of 0.05 means a 5% chance that two things are associated by coincidence or random chance. Select one: O a. There is a 1.02 x 10-8% probability that the T:T SNP is associated with distance aptitude by coincidence. This is much less than the maximum 5% probability (p=0.05) threshold needed for significance; therefore, this is significant. O b. There is a 1.02 x 10-8% probability that the C:C SNP is associated with distance aptitude by coincidence. This is much less than the maximum 5% probability (p=0.05) threshold needed for significance; therefore, this is significant. c. There is a 1.02 x 10-10% probability that the T:T SNP is associated with distance aptitude by coincidence. This is much less than the maximum 1% probability (p=0.01) threshold needed for significance; therefore, this is significant. O d. There is a 1.02 x 10-10% probability that the T:T SNP is associated with distance aptitude by coincidence. This is much less than the maximum 5% probability (p=0.05) threshold needed for significance; therefore, this is significant.
Like whippets, Thoroughbred horses have been intensely bred and selected primarily for speed by humans. Unlike whippets, Thoroughbred horses race shorter or longer races. The ability to successfully race a long distance is called "distance aptitude". Short races that have increased in popularity since the 19th century favor sprinters. A GWAS study found a g.66493737C>T SNP association with distance aptitude that had a p value of 1.02 x 10-10. In other words, the presence of a T SNP, rather than a C SNP, is associated with distance aptitude with a p value of 1.02 x 10-10. On average the optimum racing distance for C:C horses was 6.2 ± 0.8 furlongs, for C:T horses was 9.1 ± 2.4 furlongs and for T:T horses was 10.5 ± 2.7 furlongs. Furthermore, C:C horses have significantly greater muscle mass than T:T horses at two-years-old, indicating that the C SNP negatively affects myostatin. Which statement is correct regarding whether the g.66493737C>T SNP association with distance aptitude is significant or not in terms of the exact probability that the T:T SNP is associated with distance aptitude by coincidence, or random chance. Keep in mind that a p value of 0.05 means a 5% chance that two things are associated by coincidence or random chance. Select one: O a. There is a 1.02 x 10-8% probability that the T:T SNP is associated with distance aptitude by coincidence. This is much less than the maximum 5% probability (p=0.05) threshold needed for significance; therefore, this is significant. O b. There is a 1.02 x 10-8% probability that the C:C SNP is associated with distance aptitude by coincidence. This is much less than the maximum 5% probability (p=0.05) threshold needed for significance; therefore, this is significant. c. There is a 1.02 x 10-10% probability that the T:T SNP is associated with distance aptitude by coincidence. This is much less than the maximum 1% probability (p=0.01) threshold needed for significance; therefore, this is significant. O d. There is a 1.02 x 10-10% probability that the T:T SNP is associated with distance aptitude by coincidence. This is much less than the maximum 5% probability (p=0.05) threshold needed for significance; therefore, this is significant.
A First Course in Probability (10th Edition)
10th Edition
ISBN:9780134753119
Author:Sheldon Ross
Publisher:Sheldon Ross
Chapter1: Combinatorial Analysis
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Transcribed Image Text:Like whippets, Thoroughbred horses have been intensely bred and selected primarily for speed by
humans. Unlike whippets, Thoroughbred horses race shorter or longer races. The ability to
successfully race a long distance is called "distance aptitude". Short races that have increased in
popularity since the 19th century favor sprinters.
A GWAS study found a g.66493737C>T SNP association with distance aptitude that had a p value of
1.02 x 10-10. In other words, the presence of a T SNP, rather than a C SNP, is associated with distance
aptitude with a p value of 1.02 x 10-10. On average the optimum racing distance for C:C horses was
6.2 ± 0.8 furlongs, for C:T horses was 9.1 ± 2.4 furlongs and for T:T horses was 10.5 ± 2.7 furlongs.
Furthermore, C:C horses have significantly greater muscle mass than T:T horses at two-years-old,
indicating that the C SNP negatively affects myostatin.
Which statement is correct regarding whether the g.66493737C>T SNP association with distance
aptitude is significant or not in terms of the exact probability that the T:T SNP is associated with
distance aptitude by coincidence, or random chance. Keep in mind that a p value of 0.05 means a 5%
chance that two things are associated by coincidence or random chance.
Select one:
O a. There is a 1.02 x 10-8% probability that the T:T SNP is associated with distance aptitude by coincidence. This is much less than the maximum
5% probability (p=0.05) threshold needed for significance; therefore, this is significant.
O b. There is a 1.02 x 10-8% probability that the C:C SNP is associated with distance aptitude by coincidence. This is much less than the maximum
5% probability (p=0.05) threshold needed for significance; therefore, this is significant.
c. There is a 1.02 x 10-10% probability that the T:T SNP is associated with distance aptitude by coincidence. This is much less than the maximum
1% probability (p=0.01) threshold needed for significance; therefore, this is significant.
O d. There is a 1.02 x 10-10% probability that the T:T SNP is associated with distance aptitude by coincidence. This is much less than the maximum
5% probability (p=0.05) threshold needed for significance; therefore, this is significant.
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