23. In this dimethyl sulfate (DMS) chemical probing reaction, alkylation occurs at the N1 of adenosine or the N3 of cytidine to disrupt W-C pairing. Use electron pushing arrows (in at least 2 steps) to draw the chemical mechanism for how either the A or C nucleobases become methylated (do not draw ribose/backbone moieties). Indicate the charge of the methylated nitrogen. DMS N-H- H3C CH3 A N---. N=/1 H. N-H- R
Coding Strand of DNA
When pointing to DNA transcription, the coding strand is found to be the DNA strand whose base sequence is indistinguishable from the base sequence of the RNA transcript developed. It is this strand that comprises the codons, while the non-coding strand comprises the anti-codons.
Nucleotide
Both DNA and RNA are composed of organic molecules known as nucleotides. Hence, nucleotides are known as the basic building blocks of nucleic acids. These substances play a role in various processes such as cell signalling, enzyme reactions, metabolism, and so on.
Structure of Cytosine
Cytosine is among the five primary nitrogenous bases of which DNA and RNA and are being used in storage and transportation of genetic makeup within a cell. Adenine, guanine, thymine as well as uracil are the remaining four nucleobases.
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