Below is a portion of the respiration pathway in O.Extremus in which electrons are transferred from NADH to O2; the energy of this reaction is coupled to the pumping of H", and ultimately ATP production. Drug A Drug B NADH + H* FADH2 H2O 2e harvested from glucose 2e 2e electron transport NAD* FAD O2 H+ (in mitochondrial matrix) (in mitochondrial intermembrane space) АТР synthase ATP ADP+P; c) To learn more about the role of the electron transport chain in generating energy during respiration in this organism, you use two drugs. These drugs can each pick up electrons from specific intermediates in the pathway as shown above. You treat cells carrying out respiration with either a saturating dose of drug A or B, so that all the electrons which would normally continue along the pathway are captured by the drug in question. Complete the following table In the Will the cells Will the cells continue to consume O2? Yes or No continue to produce CO2? Yes or No Will the rate of ATP synthesis increase, decrease, or stay the same? Explain your reasoning. presence of ... Drug A Drug B

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 15P
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Practice question 3
Below is a portion of the respiration pathway in O.Extremus in which electrons are transferred from
NADH to O2; the energy of this reaction is coupled to the pumping of H", and ultimately ATP
production.
Drug A
Drug B
NADH + H*
FADH,
2e
2e
harvested
2e,
electron transport
from glucose
NAD+
FAD
O2
H+
(in mitochondrial matrix)
(in mitochondrial intermembrane space)
АТР
synthase
АТР
ADP+P¡
c) To learn more about the role of the electron transport chain in generating energy during respiration
in this organism, you use two drugs. These drugs can each pick up electrons from specific
intermediates in the pathway as shown above.
You treat cells carrying out respiration with either a saturating dose of drug A or B, so that all the
electrons which would normally continue along the pathway are captured by the drug in question.
Complete the following table
In the
Will the rate of ATP synthesis increase,
decrease, or stay the same?
Explain your reasoning.
Will the cells
Will the cells
continue to
continue to
presence
of ..
consume O2?
Yes or No
produce CO2?
Yes or No
Drug A
Drug B
Transcribed Image Text:Practice question 3 Below is a portion of the respiration pathway in O.Extremus in which electrons are transferred from NADH to O2; the energy of this reaction is coupled to the pumping of H", and ultimately ATP production. Drug A Drug B NADH + H* FADH, 2e 2e harvested 2e, electron transport from glucose NAD+ FAD O2 H+ (in mitochondrial matrix) (in mitochondrial intermembrane space) АТР synthase АТР ADP+P¡ c) To learn more about the role of the electron transport chain in generating energy during respiration in this organism, you use two drugs. These drugs can each pick up electrons from specific intermediates in the pathway as shown above. You treat cells carrying out respiration with either a saturating dose of drug A or B, so that all the electrons which would normally continue along the pathway are captured by the drug in question. Complete the following table In the Will the rate of ATP synthesis increase, decrease, or stay the same? Explain your reasoning. Will the cells Will the cells continue to continue to presence of .. consume O2? Yes or No produce CO2? Yes or No Drug A Drug B
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