Below are data from a study of gas exchange physiology of three different breeds of domesticated yaks from Tibet. The different breeds live at different altitudes. Note MCH is the average amount of hemoglobin contained in each red blood cell, while MCHC is the average concentration of hemoglobin in a given volume of red blood cells. Table 2 Summary of hematological parameters of the study animals expressed as the mean and standard deviation (mean ± SD). Altitude (m) RBC (10¹2/L) HCT (%) MCV (fl) MCH (pg) MCHC (g/dl) Hb (g/dl) 5100 9.34 0.45b 49.63 +2.85b 51.22 1.17 12.94 1.56 Blood volume (ml/kg) Plasma volume (ml/kg) Erythrocyte volume (ml/kg) 462.5618.76³ 13.21±0.81b Table 4 Blood volume and enzyme activity in yaks at different altitudes (mean±SD). Altitude (m) 5100 3585 96.93 +2.66 64.584.75 42.07 3.78 6.25 +0.39⁰ 5582.72 +331.49 5.94 0.37 7.34 +0.61ª 42.76 ± 2.31³ 59.62±2.39ª 14.49± 1.10 439.71 +24.27ª 10.67 + 1.07ª RBC=red blood cell count; Hct-hematocrit; Hb-hemoglobin; MCV= mean cell volume; MCH-mean corpuscular hemoglobin; and MCHC= mean corpuscular hemoglobin concentration. Means within a row with different superscripts differ (P<0.05). Lactate activity (mmol/L) Serum LDH (U/L) 2,3-DPG (pmol/g Hb) Means within a row with different superscripts differ (P<0.05). 3585 88.07 5.16 60.95 3.30 38.49±2.39 4.42 +0.35* 4381.52 287.83 2960 4.83±0.24 6.77 ± 0.33º 36.52 ± 4.24 61.94±2.78 15.45 +2.11b 386.23 +7.39b 10.16± 0.49ª 2960 80.38 4.34 59.314.24 32.35 1.17 3.51 0.37 3449.75 224.08 4.26±0.25 A. Based on our discussion of circulation and gas exchange, explain the differences that we see in the data among the different breeds of yaks. B. What experiment would you need to do or what data would you need to collect to determine whether the differences in gas exchange physiology among the different
Below are data from a study of gas exchange physiology of three different breeds of domesticated yaks from Tibet. The different breeds live at different altitudes. Note MCH is the average amount of hemoglobin contained in each red blood cell, while MCHC is the average concentration of hemoglobin in a given volume of red blood cells. Table 2 Summary of hematological parameters of the study animals expressed as the mean and standard deviation (mean ± SD). Altitude (m) RBC (10¹2/L) HCT (%) MCV (fl) MCH (pg) MCHC (g/dl) Hb (g/dl) 5100 9.34 0.45b 49.63 +2.85b 51.22 1.17 12.94 1.56 Blood volume (ml/kg) Plasma volume (ml/kg) Erythrocyte volume (ml/kg) 462.5618.76³ 13.21±0.81b Table 4 Blood volume and enzyme activity in yaks at different altitudes (mean±SD). Altitude (m) 5100 3585 96.93 +2.66 64.584.75 42.07 3.78 6.25 +0.39⁰ 5582.72 +331.49 5.94 0.37 7.34 +0.61ª 42.76 ± 2.31³ 59.62±2.39ª 14.49± 1.10 439.71 +24.27ª 10.67 + 1.07ª RBC=red blood cell count; Hct-hematocrit; Hb-hemoglobin; MCV= mean cell volume; MCH-mean corpuscular hemoglobin; and MCHC= mean corpuscular hemoglobin concentration. Means within a row with different superscripts differ (P<0.05). Lactate activity (mmol/L) Serum LDH (U/L) 2,3-DPG (pmol/g Hb) Means within a row with different superscripts differ (P<0.05). 3585 88.07 5.16 60.95 3.30 38.49±2.39 4.42 +0.35* 4381.52 287.83 2960 4.83±0.24 6.77 ± 0.33º 36.52 ± 4.24 61.94±2.78 15.45 +2.11b 386.23 +7.39b 10.16± 0.49ª 2960 80.38 4.34 59.314.24 32.35 1.17 3.51 0.37 3449.75 224.08 4.26±0.25 A. Based on our discussion of circulation and gas exchange, explain the differences that we see in the data among the different breeds of yaks. B. What experiment would you need to do or what data would you need to collect to determine whether the differences in gas exchange physiology among the different
Basic Clinical Laboratory Techniques 6E
6th Edition
ISBN:9781133893943
Author:ESTRIDGE
Publisher:ESTRIDGE
Chapter2: Basic Hematology
Section2.2: Hemoglobin
Problem 5RQ
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