Below are data from a study of gas exchange physiology of three different breeds of domesticated yaks from Tibet. The different breeds live at different altitudes. Note MCH is the average amount of hemoglobin contained in each red blood cell, while MCHC is the average concentration of hemoglobin in a given volume of red blood cells. Table 2 Summary of hematological parameters of the study animals expressed as the mean and standard deviation (mean ± SD). Altitude (m) RBC (10¹2/L) HCT (%) MCV (fl) MCH (pg) MCHC (g/dl) Hb (g/dl) 5100 9.34 0.45b 49.63 +2.85b 51.22 1.17 12.94 1.56 Blood volume (ml/kg) Plasma volume (ml/kg) Erythrocyte volume (ml/kg) 462.5618.76³ 13.21±0.81b Table 4 Blood volume and enzyme activity in yaks at different altitudes (mean±SD). Altitude (m) 5100 3585 96.93 +2.66 64.584.75 42.07 3.78 6.25 +0.39⁰ 5582.72 +331.49 5.94 0.37 7.34 +0.61ª 42.76 ± 2.31³ 59.62±2.39ª 14.49± 1.10 439.71 +24.27ª 10.67 + 1.07ª RBC=red blood cell count; Hct-hematocrit; Hb-hemoglobin; MCV= mean cell volume; MCH-mean corpuscular hemoglobin; and MCHC= mean corpuscular hemoglobin concentration. Means within a row with different superscripts differ (P<0.05). Lactate activity (mmol/L) Serum LDH (U/L) 2,3-DPG (pmol/g Hb) Means within a row with different superscripts differ (P<0.05). 3585 88.07 5.16 60.95 3.30 38.49±2.39 4.42 +0.35* 4381.52 287.83 2960 4.83±0.24 6.77 ± 0.33º 36.52 ± 4.24 61.94±2.78 15.45 +2.11b 386.23 +7.39b 10.16± 0.49ª 2960 80.38 4.34 59.314.24 32.35 1.17 3.51 0.37 3449.75 224.08 4.26±0.25 A. Based on our discussion of circulation and gas exchange, explain the differences that we see in the data among the different breeds of yaks. B. What experiment would you need to do or what data would you need to collect to determine whether the differences in gas exchange physiology among the different

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter11: The Blood
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Problem 1SQE
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Below are data from a study of gas exchange
physiology of three different breeds of
domesticated yaks from Tibet. The different
breeds live at different altitudes. Note MCH is
the average amount of hemoglobin contained in
each red blood cell, while MCHC is the average
concentration of hemoglobin in a given volume
of red blood cells.
Table 2
Summary of hematological parameters of the study animals expressed
as the mean and standard deviation (mean ± SD).
Altitude (m)
RBC (10¹2/L)
HCT (%)
MCV (fl)
MCH (pg)
MCHC (g/dl)
Hb (g/dl)
5100
9.34 +0.45b
49.63±2.85b
51.22 +1.17b
12.94 +1.56¹
Blood volume (ml/kg)
Plasma volume (ml/kg)
Erythrocyte volume (ml/kg)
462.5618.76
13.21±0.81b
Table 4
Blood volume and enzyme activity in yaks at different altitudes (mean ± SD).
Altitude (m)
5100
96.93±2.66
64.58 4.75
42.07 3.78
3585
6.25 +0.39⁰
5582.72+ 331.49
5.94+0.37b
7.34 ± 0.61¹
42.76 ±2.31³
59.62 +2.39ª
14.49 1.10
439.71 +24.27²
10.67+ 1.07ª
Lactate activity (mmol/L)
Serum LDH (U/L)
2,3-DPG (pmol/g Hb)
Means within a row with different superscripts differ (P<0.05).
RBC=red blood cell count; Hct=hematocrit; Hb-hemoglobin; MCV=
mean cell volume; MCH=mean corpuscular hemoglobin; and MCHC=
mean corpuscular hemoglobin concentration.
Means within a row with different superscripts differ (P<0.05).
3585
88.07 5.16*
60.95 +3.30
38.49±2.39
2960
4.42± 0.35
4381.52 +287.83
4.83 0.24
6.77 +0.33º
36.52 +4.24€
61.94±2.78²
15.45 +2.11b
386.23±7.39
10.16 +0.49ª
2960
80.38 +4.34°
59.31 +424
32.35± 1.17
3.51 +0.37
3449.75 +224.08*
4.26±0.25*
A. Based on our discussion of circulation and
gas exchange, explain the differences that we
see in the data among the different breeds of
yaks.
B. What experiment would you need to do or
what data would you need to collect to
determine whether the differences in gas
exchange physiology among the different
Transcribed Image Text:Below are data from a study of gas exchange physiology of three different breeds of domesticated yaks from Tibet. The different breeds live at different altitudes. Note MCH is the average amount of hemoglobin contained in each red blood cell, while MCHC is the average concentration of hemoglobin in a given volume of red blood cells. Table 2 Summary of hematological parameters of the study animals expressed as the mean and standard deviation (mean ± SD). Altitude (m) RBC (10¹2/L) HCT (%) MCV (fl) MCH (pg) MCHC (g/dl) Hb (g/dl) 5100 9.34 +0.45b 49.63±2.85b 51.22 +1.17b 12.94 +1.56¹ Blood volume (ml/kg) Plasma volume (ml/kg) Erythrocyte volume (ml/kg) 462.5618.76 13.21±0.81b Table 4 Blood volume and enzyme activity in yaks at different altitudes (mean ± SD). Altitude (m) 5100 96.93±2.66 64.58 4.75 42.07 3.78 3585 6.25 +0.39⁰ 5582.72+ 331.49 5.94+0.37b 7.34 ± 0.61¹ 42.76 ±2.31³ 59.62 +2.39ª 14.49 1.10 439.71 +24.27² 10.67+ 1.07ª Lactate activity (mmol/L) Serum LDH (U/L) 2,3-DPG (pmol/g Hb) Means within a row with different superscripts differ (P<0.05). RBC=red blood cell count; Hct=hematocrit; Hb-hemoglobin; MCV= mean cell volume; MCH=mean corpuscular hemoglobin; and MCHC= mean corpuscular hemoglobin concentration. Means within a row with different superscripts differ (P<0.05). 3585 88.07 5.16* 60.95 +3.30 38.49±2.39 2960 4.42± 0.35 4381.52 +287.83 4.83 0.24 6.77 +0.33º 36.52 +4.24€ 61.94±2.78² 15.45 +2.11b 386.23±7.39 10.16 +0.49ª 2960 80.38 +4.34° 59.31 +424 32.35± 1.17 3.51 +0.37 3449.75 +224.08* 4.26±0.25* A. Based on our discussion of circulation and gas exchange, explain the differences that we see in the data among the different breeds of yaks. B. What experiment would you need to do or what data would you need to collect to determine whether the differences in gas exchange physiology among the different
RBC (10¹2/L)
HCT (%)
MCV (fl)
MCH (pg)
MCHC (g/dl)
Hb (g/dl)
9.34 +0.45b
49.63 +2.85b
51.22 +1.17b
12.94 +1.56ª
59.62±2.39ª
14.49 + 1.10
462.5618.76³
439.71±24.27ª
13.21 +0.81b 10.67 +1.07ª
Blood volume (ml/kg)
Plasma volume (ml/kg)
Erythrocyte volume (ml/kg)
Table 4
Blood volume and enzyme activity in yaks at different altitudes (mean ± SD).
Altitude (m)
RBC=red blood cell count; Hct=hematocrit; Hb-hemoglobin; MCV=
mean cell volume; MCH=mean corpuscular hemoglobin; and MCHC=
mean corpuscular hemoglobin concentration.
Means within a row with different superscripts differ (P<0.05).
5100
96.93±2.66
64.58 +4.75
42.07 3.78
7.34 ± 0.61ª
42.76 ±2.31ª
Lactate activity (mmol/L)
Serum LDH (U/L)
2,3-DPG (pmol/g Hb)
Means within a row with different superscripts differ (P<0.05).
6.25 +0.39
5582.72331.49⁰
5.94±0.37b
3585
88.07 +5.16
60.95 3.30
38.49±2.39b
6.77 ± 0.33º
36.52 +4.24
4.42 +0.35
4381.52 +287.83€
4.83±0.24bc
61.94 +2.78a
15.45 +2.11b
386.23 +7.39b
10.16 +0.49a
2960
80.384.34
59.31 +4.24
32.35 1.17ª
3.51 +0.37
3449.75 +224.08
4.26±0.250
A. Based on our discussion of circulation and
gas exchange, explain the differences that we
see in the data among the different breeds of
yaks.
B. What experiment would you need to do or
what data would you need to collect to
determine whether the differences in gas
exchange physiology among the different
breeds of yaks is due to adaptation or
acclimation? Be sure to include the expected
outcomes that would be consistent with each
hypothesis (adaptation or acclimation).
Transcribed Image Text:RBC (10¹2/L) HCT (%) MCV (fl) MCH (pg) MCHC (g/dl) Hb (g/dl) 9.34 +0.45b 49.63 +2.85b 51.22 +1.17b 12.94 +1.56ª 59.62±2.39ª 14.49 + 1.10 462.5618.76³ 439.71±24.27ª 13.21 +0.81b 10.67 +1.07ª Blood volume (ml/kg) Plasma volume (ml/kg) Erythrocyte volume (ml/kg) Table 4 Blood volume and enzyme activity in yaks at different altitudes (mean ± SD). Altitude (m) RBC=red blood cell count; Hct=hematocrit; Hb-hemoglobin; MCV= mean cell volume; MCH=mean corpuscular hemoglobin; and MCHC= mean corpuscular hemoglobin concentration. Means within a row with different superscripts differ (P<0.05). 5100 96.93±2.66 64.58 +4.75 42.07 3.78 7.34 ± 0.61ª 42.76 ±2.31ª Lactate activity (mmol/L) Serum LDH (U/L) 2,3-DPG (pmol/g Hb) Means within a row with different superscripts differ (P<0.05). 6.25 +0.39 5582.72331.49⁰ 5.94±0.37b 3585 88.07 +5.16 60.95 3.30 38.49±2.39b 6.77 ± 0.33º 36.52 +4.24 4.42 +0.35 4381.52 +287.83€ 4.83±0.24bc 61.94 +2.78a 15.45 +2.11b 386.23 +7.39b 10.16 +0.49a 2960 80.384.34 59.31 +4.24 32.35 1.17ª 3.51 +0.37 3449.75 +224.08 4.26±0.250 A. Based on our discussion of circulation and gas exchange, explain the differences that we see in the data among the different breeds of yaks. B. What experiment would you need to do or what data would you need to collect to determine whether the differences in gas exchange physiology among the different breeds of yaks is due to adaptation or acclimation? Be sure to include the expected outcomes that would be consistent with each hypothesis (adaptation or acclimation).
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