Be sure to answer all parts. Synthesize the following compound from acetylene. You may use any other organic or inorganic reagents. ů Step 1: O HC=CH Intermediate 1: Step 2: O HC=CH draw structure ... Intermediate 2: Step 3: O CH3 CH₂ CH₂ Cl HBr NaH draw structure ... H₂O H₂SO4 HgSO4 H₂O NaH OH (dilute) O HC=CH HC=CH HOCH₂ CH₂ CH₂ Cl > O CH3 CH₂ CH₂ CI HOCH₂ CH₂ CH₂ Cl O HOCH₂ CH₂ CH₂ Cl [1] BH3 [2] H₂O₂, HO HBr

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HW 11#17

 

# Synthesis from Acetylene

## Objective

Synthesize the following compound from acetylene. You may use any other organic or inorganic reagents. The target compound is depicted as a molecule with a carbonyl group and a four-carbon chain.

## Step-by-Step Synthesis

### Step 1

1. **Reaction Setup**: 
   - Reagents Available: NaH, HBr

2. **Reactions Overview**:
   - HC≡CH (acetylene) reacts with HBr to produce HOCH₂CH₂CH₂Cl.
   - HC≡CH reacts through a pathway that involves interaction with different structures to result in the selected product.

3. **Correct Path**:
   - Use HBr with acetylene to form the intermediate HOCH₂CH₂CH₂Cl.

### Intermediate 1

- At this stage, the intermediate molecule is required for further reactions.
- The correct intermediate structure is selected via "draw structure."

### Step 2

1. **Reaction Setup**:
   - Reagents available: HBr, NaH

2. **Reactions Overview**:
   - HBr can lead to HOCH₂CH₂CH₂Cl.
   - NaH can lead to CH₃CH₂CH₂Cl.

3. **Correct Path**:
   - Select the pathway using HBr to form the desired intermediate product.

### Intermediate 2

- Draw the structure to proceed to the next reaction stage.

### Step 3

1. **Reaction Setup**:
   - Reagents available: H₂O, H₂SO₄, HgSO₄, and [1] BH₃ followed by [2] H₂O₂, HO⁻

2. **Reactions Overview**:
   - Use H₂O with H₂SO₄, HgSO₄ to move towards the desired carbonyl compound.
   - Alternatively, [1] BH₃ and [2] H₂O₂, HO⁻ can also direct the synthesis.

3. **Correct Path**:
   - Select the addition of water (H₂O) to achieve the final desired product.

## Conclusion

Through these steps, you synthesize the target carbonyl compound starting from acetylene by selecting appropriate reagents and reaction pathways. Each step involves careful consideration of intermediary structures and final product formation.
Transcribed Image Text:# Synthesis from Acetylene ## Objective Synthesize the following compound from acetylene. You may use any other organic or inorganic reagents. The target compound is depicted as a molecule with a carbonyl group and a four-carbon chain. ## Step-by-Step Synthesis ### Step 1 1. **Reaction Setup**: - Reagents Available: NaH, HBr 2. **Reactions Overview**: - HC≡CH (acetylene) reacts with HBr to produce HOCH₂CH₂CH₂Cl. - HC≡CH reacts through a pathway that involves interaction with different structures to result in the selected product. 3. **Correct Path**: - Use HBr with acetylene to form the intermediate HOCH₂CH₂CH₂Cl. ### Intermediate 1 - At this stage, the intermediate molecule is required for further reactions. - The correct intermediate structure is selected via "draw structure." ### Step 2 1. **Reaction Setup**: - Reagents available: HBr, NaH 2. **Reactions Overview**: - HBr can lead to HOCH₂CH₂CH₂Cl. - NaH can lead to CH₃CH₂CH₂Cl. 3. **Correct Path**: - Select the pathway using HBr to form the desired intermediate product. ### Intermediate 2 - Draw the structure to proceed to the next reaction stage. ### Step 3 1. **Reaction Setup**: - Reagents available: H₂O, H₂SO₄, HgSO₄, and [1] BH₃ followed by [2] H₂O₂, HO⁻ 2. **Reactions Overview**: - Use H₂O with H₂SO₄, HgSO₄ to move towards the desired carbonyl compound. - Alternatively, [1] BH₃ and [2] H₂O₂, HO⁻ can also direct the synthesis. 3. **Correct Path**: - Select the addition of water (H₂O) to achieve the final desired product. ## Conclusion Through these steps, you synthesize the target carbonyl compound starting from acetylene by selecting appropriate reagents and reaction pathways. Each step involves careful consideration of intermediary structures and final product formation.
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