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Based on the experience of the Philippines with the dengue vaccine, what can you conclude regarding the use of vaccines?  a. Vaccines should be tested for long period of time before allowing any individual to take the vaccine. b. All aspects as on the long-term effects of vaccines, its effect on children, pregnant women, effect to reproductive system, immediate side effects and many more should be analysed first. c. Vaccines take time to be developed and studied for their effectivity and effects. d. All vaccines have side effects, only few individuals should have them. e. Vaccines that were tested for decades could be trusted for its safety but still precaution should be observed.

Based on the experience of the Philippines with the dengue vaccine, what can you conclude regarding the use of vaccines?  a. Vaccines should be tested for long period of time before allowing any individual to take the vaccine. b. All aspects as on the long-term effects of vaccines, its effect on children, pregnant women, effect to reproductive system, immediate side effects and many more should be analysed first. c. Vaccines take time to be developed and studied for their effectivity and effects. d. All vaccines have side effects, only few individuals should have them. e. Vaccines that were tested for decades could be trusted for its safety but still precaution should be observed.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Based on the experience of the Philippines with the dengue vaccine, what can you conclude regarding the use of vaccines? 


a. Vaccines should be tested for long period of time before allowing any individual to take the vaccine.
b. All aspects as on the long-term effects of vaccines, its effect on children, pregnant women, effect to reproductive system, immediate side effects and many more should be analysed first.
c. Vaccines take time to be developed and studied for their effectivity and effects.
d. All vaccines have side effects, only few individuals should have them.
e. Vaccines that were tested for decades could be trusted for its safety but still precaution should be observed.

Terms: Seronegative: Individuals who had never been infected by dengue virus. Fact 1: The program on the study for the production of dengue vaccine started in 1920. Vaccines are usually produced with minimum of 5 years of clinical trials. Fact 2: Dengvaxia, a dengue vaccine produced by Sanofi Pharmaceuticals, became commercially available in 2015 and 2016, in 11 countries: Mexico, the Philippines, Indonesia, Brazil, El Salvador, Costa Rica, Paraguay, Guatemala, Peru, Thailand, and Singapore. Fact 3: Trade named Dengvaxia, it is approved for use for those aged nine and older and can prevent all four serotypes resulting from high efficacy rate in its trial use. Fact 4: In 2017, the manufacturer recommended that the vaccine only be used in people who have previously had a dengue infection, as outcomes may be worsened in those who have not been previously infected. Fact 5: The World Health Organization (WHO) recommends that countries should consider vaccination with the dengue vaccine only if the risk of severe dengue in seronegative individuals can be minimized. In September 2018, WHO updated its recommendation based on the evidence that seronegative vaccine recipients have an excess risk of severe dengue compared to unvaccinated seronegative individuals. Fact 6: More than 733,000 children and more than 50,000 adult volunteers were vaccinated with dengue vaccine in the Philippines. Some who received the vaccine had never been infected by the dengue virus before. Fact 7: It is still unknown if Sanofi did not inform the Philippine government of the precautions or that the Phil government and doctors neglected to implement necessary precautions such as sero-testing before vaccination. Fact 8: Some claims that children who were vaccinated with the Dengvaxia died due to complications caused by the vaccine. As of now, investigations and judicial trial is on progress. Fact 9: No controversy on the dengvaxia vaccines in other countries where it was approved.
Transcribed Image Text:Terms: Seronegative: Individuals who had never been infected by dengue virus. Fact 1: The program on the study for the production of dengue vaccine started in 1920. Vaccines are usually produced with minimum of 5 years of clinical trials. Fact 2: Dengvaxia, a dengue vaccine produced by Sanofi Pharmaceuticals, became commercially available in 2015 and 2016, in 11 countries: Mexico, the Philippines, Indonesia, Brazil, El Salvador, Costa Rica, Paraguay, Guatemala, Peru, Thailand, and Singapore. Fact 3: Trade named Dengvaxia, it is approved for use for those aged nine and older and can prevent all four serotypes resulting from high efficacy rate in its trial use. Fact 4: In 2017, the manufacturer recommended that the vaccine only be used in people who have previously had a dengue infection, as outcomes may be worsened in those who have not been previously infected. Fact 5: The World Health Organization (WHO) recommends that countries should consider vaccination with the dengue vaccine only if the risk of severe dengue in seronegative individuals can be minimized. In September 2018, WHO updated its recommendation based on the evidence that seronegative vaccine recipients have an excess risk of severe dengue compared to unvaccinated seronegative individuals. Fact 6: More than 733,000 children and more than 50,000 adult volunteers were vaccinated with dengue vaccine in the Philippines. Some who received the vaccine had never been infected by the dengue virus before. Fact 7: It is still unknown if Sanofi did not inform the Philippine government of the precautions or that the Phil government and doctors neglected to implement necessary precautions such as sero-testing before vaccination. Fact 8: Some claims that children who were vaccinated with the Dengvaxia died due to complications caused by the vaccine. As of now, investigations and judicial trial is on progress. Fact 9: No controversy on the dengvaxia vaccines in other countries where it was approved.
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