base* = K₂CO3 or CaCO3 L = ligand biaryl product (~ 92%)

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter16: Chemistry Of Benzene: Electrophilic Aromatic Substitution
Section16.SE: Something Extra
Problem 30MP: The carbocation electrophile in a Friede1-Crafts reaction can be generated by an alternate means...
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Can you show the mechanism for this example of Suzuki miyaura?

SUZUKI-MIYAURA REACTION:
Br
+
bromobenzene;
Aryl or vinyl halide
proposed mechanism:
RO.
RO
an alkyl, alkenyl or aryl-
organoboron compound
B-
PdL 2
base*
*
base* = K₂CO3 or CaCO3
=
biaryl product (~ 92%)
Transcribed Image Text:SUZUKI-MIYAURA REACTION: Br + bromobenzene; Aryl or vinyl halide proposed mechanism: RO. RO an alkyl, alkenyl or aryl- organoboron compound B- PdL 2 base* * base* = K₂CO3 or CaCO3 = biaryl product (~ 92%)
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