Barbara and John have two daughters (Madison and Kelly), and one son (Mike), all have normal red blood cells. Their other son (Chase) has been diagnosed with sickle cell. Barbara recently gave birth to another son (Barry) who also has been diagnosed with sickle cell. Barbara’s mother (Beth) has sickle cell, but her father (Jason), three sisters (Emma, Lori, and Allison), and two brothers (Emmitt and Will) are all normal. John’s father (Jim), mother (Brenda), and brother (Parker) are all normal, but his sister (Demi) has sickle cell. John’s maternal grandparents (Bill and Lonna) are carriers. Barbara’s paternal grandparents (Kevin and Martha) are all normal Paternal = a person’s dad’s side of the family Maternal = a person’s mom’s side of the family 1. Draw a pedigree to show how this trait could affect this family within each generation 2. Shade all individuals affected with the disorder. Half shade all carriers. 3. Assign genotypes to every individual. Use Punnett squares to support your predictions if needed. 4. Label all generations and each individual throughout your pedigree. 5. List the names of all individuals that have been affected by the disorder 6. List the names of all individuals who are listed carriers. 7. List the names of all potential carriers.
Barbara and John have two daughters (Madison and Kelly), and one son (Mike), all have normal red blood cells. Their other son (Chase) has been diagnosed with sickle cell. Barbara recently gave birth to another son (Barry) who also has been diagnosed with sickle cell. Barbara’s mother (Beth) has sickle cell, but her father (Jason), three sisters (Emma, Lori, and Allison), and two brothers (Emmitt and Will) are all normal. John’s father (Jim), mother (Brenda), and brother (Parker) are all normal, but his sister (Demi) has sickle cell. John’s maternal grandparents (Bill and Lonna) are carriers. Barbara’s paternal grandparents (Kevin and Martha) are all normal
Paternal = a person’s dad’s side of the family
Maternal = a person’s mom’s side of the family
1. Draw a pedigree to show how this trait could affect this family within each generation
2. Shade all individuals affected with the disorder. Half shade all carriers.
3. Assign genotypes to every individual. Use Punnett squares to support your predictions if needed.
4. Label all generations and each individual throughout your pedigree.
5. List the names of all individuals that have been affected by the disorder
6. List the names of all individuals who are listed carriers.
7. List the names of all potential carriers.
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