B1 Consider the inside and outside of a cel, where the 8-nanometer-thick cell membrane has a large number of open Na lon channels. The major contributor to these lons is dissolvedNaCL Lets analyze a "toy moder of the cell's resting potential in which the Na" lon channels are the only ion channels, they are permanontly open, and Nacl is the only oontributor ofNa* ions. Assume the outside of the cell has a concentration of 150 mM NaCI and that the concentration inside the cell is much, much lower.in this problem, use a temperature of 290K, at which kT= 0.025 K.Part AI the Nermat potential for the sodium ions in our toy model is 60 mV, what would the concentration of NoCi be on the inside of the cel? ignore the Cl iona]mMSubmitReguest AnswerPart BNow let us refine our model by noting that there is a second source of Na ions in the cell: Nal. Supposo the outside of the cell has a concentration of Nal of 0.04 mM and the insidehas a Nal concentration of 4 mM. How will the presence of these ions change the Na" Nornst potential across the membrane? (Assume the Nal io fully ionized in solution)

Here E = 60 mV or 60 × 10-3 V (as 1000mV = 1V). At T = 298 K, (2.303 × RT/F) = 0.059

Science

Chemistry

B1

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

Consider the inside and outside of a cel, where the 8-nanometer-thick cell membrane has a large number of open Na lon channels. The major contributor to these lons is dissolved
NaCL Lets analyze a "toy moder of the cell's resting potential in which the Na" lon channels are the only ion channels, they are permanontly open, and Nacl is the only oontributor of
Na* ions. Assume the outside of the cell has a concentration of 150 mM NaCI and that the concentration inside the cell is much, much lower.
in this problem, use a temperature of 290K, at which kT= 0.025 K.
Part A
I the Nermat potential for the sodium ions in our toy model is 60 mV, what would the concentration of NoCi be on the inside of the cel? ignore the Cl iona]
mM
Submit
Reguest Answer
Part B
Now let us refine our model by noting that there is a second source of Na ions in the cell: Nal. Supposo the outside of the cell has a concentration of Nal of 0.04 mM and the inside
has a Nal concentration of 4 mM. How will the presence of these ions change the Na" Nornst potential across the membrane? (Assume the Nal io fully ionized in solution)

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