b. (Requires more than 1 step!) Hints: requires more than 1 step; you may use any other reagents necessary like bases, metals, etc.; you may use work-ups as we have in the past; you may use solvents as we have in the past; you will need to use chemistry that we have studied in past units this year; remember whether nitrogen or oxygen is a better nucleophile. Lastly you will need to use the following reaction that we have not yet discussed this year! HBr with organic peroxides Br Product! `OH Salmeterol (B2 adrenoceptor agonist) QH -NH2 `OH Br но B (3 starting materials)
b. (Requires more than 1 step!) Hints: requires more than 1 step; you may use any other reagents necessary like bases, metals, etc.; you may use work-ups as we have in the past; you may use solvents as we have in the past; you will need to use chemistry that we have studied in past units this year; remember whether nitrogen or oxygen is a better nucleophile. Lastly you will need to use the following reaction that we have not yet discussed this year! HBr with organic peroxides Br Product! `OH Salmeterol (B2 adrenoceptor agonist) QH -NH2 `OH Br но B (3 starting materials)
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question
give synthesis
![b. (Requires more than 1 step!)
Hints: requires more than 1 step; you may use any other reagents necessary like bases,
metals, etc.; you may use work-ups as we have in the past; you may use solvents as we
have in the past; you will need to use chemistry that we have studied in past units this year;
remember whether nitrogen or oxygen is a better nucleophile. Lastly you will need to use
the following reaction that we have not yet discussed this year!
HBr with organic peroxides
Br
он
Product!
он
`OH
Salmeterol
(B2 adrenoceptor agonist)
он
-NH2
OH
Br
но
A
в он
(3 starting materials)](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F14494f59-88ab-4e14-bfe6-eddafc8b6be3%2Ffc7c05c7-3943-44d4-b1e7-444fe0008aa9%2Fjxbbiuh_processed.png&w=3840&q=75)
Transcribed Image Text:b. (Requires more than 1 step!)
Hints: requires more than 1 step; you may use any other reagents necessary like bases,
metals, etc.; you may use work-ups as we have in the past; you may use solvents as we
have in the past; you will need to use chemistry that we have studied in past units this year;
remember whether nitrogen or oxygen is a better nucleophile. Lastly you will need to use
the following reaction that we have not yet discussed this year!
HBr with organic peroxides
Br
он
Product!
он
`OH
Salmeterol
(B2 adrenoceptor agonist)
он
-NH2
OH
Br
но
A
в он
(3 starting materials)
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