B. Fig. 1. A: Pedigree of a Chinese family with achondroplasia. Rr R Rr RY Based on this pedigree, is achondroplasia a dominant or a recessive trait? WHY do you think that? 7. 2. RY Bused on the pedigree, 1 think it is domihant, becuuse all affected parents have atfected' children. II 3. 5. BY Br RY I also think Bused on the pedigree) it is autusomal because hoth mules 4 femules have it. III O 4. 5. 7. bp Marker III-2 П-3 III-4 III-5 III-6 III-7 600 500 400 300 200 8. Determine the possible genotype(s) for each person in the pedigree and write their genotype above the individual. Remember to take into 100 account whether achondroplasia is dominant or recessive! The proband ONormal Affacted O Female Deceased Based on the information from the pedigree and the gel electrophoresis analysis, does this mutation cause achondroplasia in this family? How can you tell? 9. bP Possible Gametes Somatic Cell 10. Show the inheritance of the FGFR3 gene from individuals II-1 and II-2 to their offspring: Draw a somatic cell from each of the two parents containing the correct chromosome (you learned the chromosome number earlier) with the FGFR3 alleles labeled and the appropriate sex chromosomes for each parent. b. Draw the possible gametes produced by each parent, again showing the correct chromosome with the FGFR3 alleles labeled and the appropriate sex chromosomes for each parent. a. Parent II-1 Parent II-2 chondrey WHY do

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The pedigree shows individual  1 and

2

B.
Fig. 1. A: Pedigree of a Chinese family with achondroplasia.
Rr
R Rr RY
Based on this pedigree, is achondroplasia a
dominant or a recessive trait? WHY do you think
that?
7.
2.
RY
Bused on the pedigree, 1 think
it is domihant, becuuse all
affected parents have
atfected' children.
II
3.
5.
BY
Br
RY
I also think Bused on the
pedigree) it is autusomal
because hoth mules 4
femules have it.
III O
4.
5.
7.
bp
Marker III-2
П-3
III-4
III-5
III-6
III-7
600
500
400
300
200
8. Determine the possible genotype(s) for each
person in the pedigree and write their genotype
above the individual. Remember to take into
100
account whether achondroplasia is dominant or
recessive!
The proband
ONormal Affacted O Female Deceased
Based on the information from the pedigree and the gel electrophoresis analysis, does this mutation cause
achondroplasia in this family? How can you tell?
9.
bP
Transcribed Image Text:B. Fig. 1. A: Pedigree of a Chinese family with achondroplasia. Rr R Rr RY Based on this pedigree, is achondroplasia a dominant or a recessive trait? WHY do you think that? 7. 2. RY Bused on the pedigree, 1 think it is domihant, becuuse all affected parents have atfected' children. II 3. 5. BY Br RY I also think Bused on the pedigree) it is autusomal because hoth mules 4 femules have it. III O 4. 5. 7. bp Marker III-2 П-3 III-4 III-5 III-6 III-7 600 500 400 300 200 8. Determine the possible genotype(s) for each person in the pedigree and write their genotype above the individual. Remember to take into 100 account whether achondroplasia is dominant or recessive! The proband ONormal Affacted O Female Deceased Based on the information from the pedigree and the gel electrophoresis analysis, does this mutation cause achondroplasia in this family? How can you tell? 9. bP
Possible Gametes
Somatic Cell
10. Show the inheritance of the FGFR3 gene from individuals II-1 and II-2 to their offspring:
Draw a somatic cell from each of the two parents containing the correct chromosome (you learned the
chromosome number earlier) with the FGFR3 alleles labeled and the appropriate sex chromosomes for each
parent.
b. Draw the possible gametes produced by each parent, again showing the correct chromosome with the FGFR3
alleles labeled and the appropriate sex chromosomes for each parent.
a.
Parent II-1
Parent II-2
chondrey
WHY do
Transcribed Image Text:Possible Gametes Somatic Cell 10. Show the inheritance of the FGFR3 gene from individuals II-1 and II-2 to their offspring: Draw a somatic cell from each of the two parents containing the correct chromosome (you learned the chromosome number earlier) with the FGFR3 alleles labeled and the appropriate sex chromosomes for each parent. b. Draw the possible gametes produced by each parent, again showing the correct chromosome with the FGFR3 alleles labeled and the appropriate sex chromosomes for each parent. a. Parent II-1 Parent II-2 chondrey WHY do
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