(b) The actual resting membrane potential of the cell is not only dependent on the individual components calculated above, but also relates to the overall permeability of the cell membrane to each of the ion types. It turns out that the majority of the total resting membrane potential for a cell (Atotal) is derived from the movement of K+ ions, accounting for ~90% of the total potential. In contrast the contribution from Na+ is ~ 1%, Ca2+ is ~1%, and for Cl- is ~8%. Given these values, and the individual A values calculated in part (a), estimate the overall membrane resting potential.

Biochemistry
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Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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use the values calculated (picture 2) to solve picture 1
(b) The actual resting membrane potential of the cell is not only dependent on the individual
components calculated above, but also relates to the overall permeability of the cell membrane
to each of the ion types. It turns out that the majority of the total resting membrane potential
for a cell (Atotal) is derived from the movement of K+ ions, accounting for ~90% of the total
potential. In contrast the contribution from Na+ is ~ 1%, Ca²+ is ~1%, and for Cl- is ~8%. Given
these values, and the individual A values calculated in part (a), estimate the overall membrane
resting potential.
Transcribed Image Text:(b) The actual resting membrane potential of the cell is not only dependent on the individual components calculated above, but also relates to the overall permeability of the cell membrane to each of the ion types. It turns out that the majority of the total resting membrane potential for a cell (Atotal) is derived from the movement of K+ ions, accounting for ~90% of the total potential. In contrast the contribution from Na+ is ~ 1%, Ca²+ is ~1%, and for Cl- is ~8%. Given these values, and the individual A values calculated in part (a), estimate the overall membrane resting potential.
4
DPK = 61.49 109 10 14
261.49 109 145
10
261,49 (-1.384)
85. ImV
61.49
|AYca =
म
2
61.49
2
= 30.745 (3.6027
11074 V
५
109%0 0.001
|AYea = =
५
10910 0.001
APNA = 61.49
n
=
145
61.49 109108
= 61.49 (1-258)
77.35 mV
Auct = 61.49
DYNA
AYC
145
109 108
१०
109106
= - 61.49 105 (15)
= -61.49 (1.176
·72.31MV
-
Transcribed Image Text:4 DPK = 61.49 109 10 14 261.49 109 145 10 261,49 (-1.384) 85. ImV 61.49 |AYca = म 2 61.49 2 = 30.745 (3.6027 11074 V ५ 109%0 0.001 |AYea = = ५ 10910 0.001 APNA = 61.49 n = 145 61.49 109108 = 61.49 (1-258) 77.35 mV Auct = 61.49 DYNA AYC 145 109 108 १० 109106 = - 61.49 105 (15) = -61.49 (1.176 ·72.31MV -
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