(b) Table Q1 below provides the results from a study of a rapid diagnostic test for tuberculosis (TB). Calculate its sensitivity and specificity. What is the likelihood that a patient tested positive with this test is infected with TB ? Groups TB Non-TB Healthy Controls Total Trustline kit, n Positive Negative 385 53 24 462 243 166 138 547 Table Q1: Clinical performance of the Trustline diagnostic kit for tuberculosis (TB). (non-TB patients are sick patients, but that do not suffer from TB). Taken from Eur J Clin Microbiol Infect Dis (2014) 33:1989-1994 Solution: Sensitivity = 61% Specificity = 79% positive predictive value 83%. So roughly out of 10 positive results, 8 patients will actually have the disease. 2 patients will be wrongly diagnosed.

Human Anatomy & Physiology (11th Edition)
11th Edition
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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How did they get 79%?
(b)
Table Q1 below provides the results from a study of a rapid diagnostic test for
tuberculosis (TB). Calculate its sensitivity and specificity. What is the
likelihood that a patient tested positive with this test is infected with TB ?
Groups
TB
Non-TB
Healthy Controls
Total
Trustline kit, n
Positive Negative
385
53
462
243
166
138
547
Table Q1: Clinical performance of the Trustline diagnostic kit for tuberculosis (TB).
(non-TB patients are sick patients, but that do not suffer from TB). Taken
from Eur J Clin Microbiol Infect Dis (2014) 33:1989-1994
Solution:
Sensitivity = 61%
Specificity = 79%
positive predictive value 83%. So roughly out of 10 positive results, 8 patients will
actually have the disease. 2 patients will be wrongly diagnosed.
Transcribed Image Text:(b) Table Q1 below provides the results from a study of a rapid diagnostic test for tuberculosis (TB). Calculate its sensitivity and specificity. What is the likelihood that a patient tested positive with this test is infected with TB ? Groups TB Non-TB Healthy Controls Total Trustline kit, n Positive Negative 385 53 462 243 166 138 547 Table Q1: Clinical performance of the Trustline diagnostic kit for tuberculosis (TB). (non-TB patients are sick patients, but that do not suffer from TB). Taken from Eur J Clin Microbiol Infect Dis (2014) 33:1989-1994 Solution: Sensitivity = 61% Specificity = 79% positive predictive value 83%. So roughly out of 10 positive results, 8 patients will actually have the disease. 2 patients will be wrongly diagnosed.
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