At what level can glucose become as osmotic diuretic? A. When Cglucose decreases B. When p[glucose] doubles from 100mg/100ml to 200mg/100ml C. When urine contains glucose D. When filtered glucose amounts increase by more than 2 fold

Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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At what level can glucose become as osmotic diuretic?
A. When Cglucose decreases
B. When p[glucose] doubles from 100mg/100ml to 200mg/100ml
C. When urine contains glucose
D. When filtered glucose amounts increase by more than 2 fold
Transcribed Image Text:At what level can glucose become as osmotic diuretic? A. When Cglucose decreases B. When p[glucose] doubles from 100mg/100ml to 200mg/100ml C. When urine contains glucose D. When filtered glucose amounts increase by more than 2 fold
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WHEN GLUCOSE BECOME AS OSMOTIC DIURETIC are as follows conditons:

  • Hyperglycemia
  • Use of certain medicines, such as Mannitol. Mannitol is a sugar alcohol that does not cross cell membranes, and acts as an osmotic diuretic that inhibits sodium and water reabsorption in the proximal tubule, as well as the loop of Henle. Mannitol produces a greater loss of water compared to sodium and potassium. The increase in urine flow also decreases the contact time between fluid and the tubular epithelium, which reduces sodium (Na) reabsorption as well as water reabsorption. This resulting loss of sodium (Na) is of lesser magnitude than the loss of water, resulting in excessive water loss and hypernatremia.
  • An osmotic diuresis may also result from excessive urea production owing to excessive protein administration.
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