Assume a biallelic locus in a diploid population. Out of 100 individuals, the following genotypes were observed: 59 A1A1 individuals; 16 A1A2 individuals; and 25 A2A2 individuals. What is the observed (actual; not predicted) allele frequency of the A1 allele? (you may use a calculator here) O A. 0.33 O B. 0.67 O C. 0.16 O D.0.59 O E. 0.25
Assume a biallelic locus in a diploid population. Out of 100 individuals, the following genotypes were observed: 59 A1A1 individuals; 16 A1A2 individuals; and 25 A2A2 individuals. What is the observed (actual; not predicted) allele frequency of the A1 allele? (you may use a calculator here) O A. 0.33 O B. 0.67 O C. 0.16 O D.0.59 O E. 0.25
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
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Transcribed Image Text:**Problem: Calculate Observed Allele Frequency**
Assume a biallelic locus in a diploid population. Out of 100 individuals, the following genotypes were observed:
- 59 A₁A₁ individuals
- 16 A₁A₂ individuals
- 25 A₂A₂ individuals
**Question:**
What is the observed (actual; not predicted) allele frequency of the A₁ allele?
(You may use a calculator here)
**Options:**
- A. 0.33
- B. 0.67
- C. 0.16
- D. 0.59
- E. 0.25
**Explanation:**
To find the allele frequency of A₁:
1. Total number of alleles in the population = 100 individuals * 2 alleles/individual = 200 alleles.
2. Number of A₁ alleles from A₁A₁ individuals = 59 individuals * 2 alleles = 118 alleles.
3. Number of A₁ alleles from A₁A₂ individuals = 16 individuals * 1 allele = 16 alleles.
4. Total number of A₁ alleles = 118 + 16 = 134 alleles.
5. Frequency of A₁ allele = Number of A₁ alleles / Total number of alleles = 134 / 200 = 0.67.
Thus, the correct answer is B. 0.67.
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