Assign stereochemical configurations (R/S) to the chiral carbons in the molecule below 2 = H = Cl = C = CH3 =CH₂CH3

Chemistry: Matter and Change
1st Edition
ISBN:9780078746376
Author:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Publisher:Dinah Zike, Laurel Dingrando, Nicholas Hainen, Cheryl Wistrom
Chapter22: Substituted Hydrocarbons And Their Reactions
Section22.1: Alkyl Halides And Aryl Halides
Problem 8SSC
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**Title: Assigning Stereochemical Configurations to Chiral Centers**

**Instruction:**
Assign stereochemical configurations (R/S) to the chiral carbons in the molecule below.

**Diagram:**
A 3D molecular model is depicted with two chiral centers labeled as "1" and "2". The molecule consists of various colored spheres representing different atoms or groups attached to the central carbon atoms.

**Description of Atoms and Groups:**
- **White sphere:** Hydrogen (H)
- **Green sphere:** Chlorine (Cl)
- **Gray sphere:** Carbon (C)
- **Purple sphere:** Methyl group (CH₃)
- **Red sphere:** Ethyl group (CH₂CH₃)

**Analysis:**
To assign the R/S configuration:
1. Identify the chiral centers (1 and 2).
2. Assign priorities to the substituents based on atomic number.
3. Arrange the molecule so that the lowest priority group (usually hydrogen) is positioned away from the viewer.
4. Determine the order of the substituents (1 to 3). If the order is clockwise, the configuration is R; if counterclockwise, it is S.

**Note:**
This exercise helps understand stereochemistry's role in determining molecular interactions and properties.
Transcribed Image Text:**Title: Assigning Stereochemical Configurations to Chiral Centers** **Instruction:** Assign stereochemical configurations (R/S) to the chiral carbons in the molecule below. **Diagram:** A 3D molecular model is depicted with two chiral centers labeled as "1" and "2". The molecule consists of various colored spheres representing different atoms or groups attached to the central carbon atoms. **Description of Atoms and Groups:** - **White sphere:** Hydrogen (H) - **Green sphere:** Chlorine (Cl) - **Gray sphere:** Carbon (C) - **Purple sphere:** Methyl group (CH₃) - **Red sphere:** Ethyl group (CH₂CH₃) **Analysis:** To assign the R/S configuration: 1. Identify the chiral centers (1 and 2). 2. Assign priorities to the substituents based on atomic number. 3. Arrange the molecule so that the lowest priority group (usually hydrogen) is positioned away from the viewer. 4. Determine the order of the substituents (1 to 3). If the order is clockwise, the configuration is R; if counterclockwise, it is S. **Note:** This exercise helps understand stereochemistry's role in determining molecular interactions and properties.
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