Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter12: Chirality
Section: Chapter Questions
Problem 29CTQ
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Transcribed Image Text:**Section IX:** Assign R, S configurations to each indicated chirality center in the molecules below.
1. **Molecule with Carbon 14**:
- Structure: Aromatic benzene ring with hydroxyl groups (OH) and an amine group (CH₂NH₂) attached.
- Assigned chirality center: Carbon 14.
2. **Molecule with Carbon 15**:
- Structure: Tetrahedral structure with a carboxylic acid group (COOH), a hydrogen, a methyl group (CH₃), and an amine group (H₂N) attached.
- Assigned chirality center: Carbon 15.
3. **Molecule with Carbon 16**:
- Structure: Molecule with a hydroxyl group (OH), a hydrogen, and two carboxylic acid groups (HO₂C and CO₂H).
- Assigned chirality center: Carbon 16.
4. **Molecule with Carbon 17 and 18**:
- Structure: Cyclohexanone ring with a ketone (C=O) and ethyl group (CH₃CH₂) attached.
- Assigned chirality centers: Carbon 17 and Carbon 18.
**Answer the following:**
- The configuration of carbon 14 is _____.
- The configuration of carbon 15 is _____.
- The configuration of carbon 16 is _____.
- The configuration of carbon 17 is _____.
- The configuration of carbon 18 is _____.
**Note:** Use the Cahn-Ingold-Prelog priority rules to determine the R (rectus) or S (sinister) configuration for each chirality center designated in the molecules.
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