As the name suggests, the stratum spinosum is spiny in appearance due to the protruding cell processes that join the cells via a structure called a desmosome. The desmosomes interlock with each other and strengthen the bond between the cells. It is interesting to note that the "spiny" nature of this layer is an artifact of the staining process. Unstained epidermis samples do not exhibit this characteristic appearance. The stratum spinosum is composed of eight to 10 layers of keratinocytes, formed as a result of cell division in the stratum basale (Figure 5.6). Interspersed among the keratinocytes of this layer is a type of dendritic cell called the Langerhans cell, which functions as a macrophage by engulfing bacteria, foreign particles, and damaged cells that occur in this layer. WebScope 1 16013 x 16013 size 733.61MB mag 20X 065 - Epidermis_001.svs Returm to image directory Epidermis Zoom Fit 2K 4X Stratum SK coneum 200 Stratum 0.7X granulosum Romnants of cross-sectioned shed hair and its follicle Stratum spinosum Stratum basale or germinativum Capillary Dermis EV Mag. 2.700 X Figure 5.6 Cells of the Epidermis The cells in the different layers of the epidermis originate from basal cells located in the stratum basale, yet the cells of each layer are distinctively different. EM x 2700. (Micrograph provided by the Regents of University of Michigan Medical School © 2012)

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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As shown If you zoom on the cells of the stratum spinosum, what is distinctive about them?

As the name suggests, the stratum spinosum is spiny in appearance due to the protruding cell processes that join the cells
via a structure called a desmosome. The desmosomes interlock with each other and strengthen the bond between the cells. It
is interesting to note that the "spiny" nature of this layer is an artifact of the staining process. Unstained epidermis samples
do not exhibit this characteristic appearance. The stratum spinosum is composed of eight to 10 layers of keratinocytes,
formed as a result of cell division in the stratum basale (Figure 5.6). Interspersed among the keratinocytes of this layer is a
type of dendritic cell called the Langerhans cell, which functions as a macrophage by engulfing bacteria, foreign particles,
and damaged cells that occur in this layer.
WebScope 1
16013 x 16013 size 733.61MB mag 20X
065 - Epidermis_001.svs
Returm to image directory
Epidermis
Zoom
Fit
2K
4X
Stratum
SK
coneum
200
Stratum
0.7X
granulosum
Romnants of
cross-sectioned
shed hair and
its follicle
Stratum
spinosum
Stratum basale
or germinativum
Capillary
Dermis
EV Mag. 2.700 X
Figure 5.6 Cells of the Epidermis The cells in the different layers of the epidermis originate from basal cells located
in the stratum basale, yet the cells of each layer are distinctively different. EM x 2700. (Micrograph provided by the
Regents of University of Michigan Medical School © 2012)
Transcribed Image Text:As the name suggests, the stratum spinosum is spiny in appearance due to the protruding cell processes that join the cells via a structure called a desmosome. The desmosomes interlock with each other and strengthen the bond between the cells. It is interesting to note that the "spiny" nature of this layer is an artifact of the staining process. Unstained epidermis samples do not exhibit this characteristic appearance. The stratum spinosum is composed of eight to 10 layers of keratinocytes, formed as a result of cell division in the stratum basale (Figure 5.6). Interspersed among the keratinocytes of this layer is a type of dendritic cell called the Langerhans cell, which functions as a macrophage by engulfing bacteria, foreign particles, and damaged cells that occur in this layer. WebScope 1 16013 x 16013 size 733.61MB mag 20X 065 - Epidermis_001.svs Returm to image directory Epidermis Zoom Fit 2K 4X Stratum SK coneum 200 Stratum 0.7X granulosum Romnants of cross-sectioned shed hair and its follicle Stratum spinosum Stratum basale or germinativum Capillary Dermis EV Mag. 2.700 X Figure 5.6 Cells of the Epidermis The cells in the different layers of the epidermis originate from basal cells located in the stratum basale, yet the cells of each layer are distinctively different. EM x 2700. (Micrograph provided by the Regents of University of Michigan Medical School © 2012)
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