ANTI - STREPTOLYSIN O TITER ASO Latex Test ASO is a rapid latex agglutination test for the detection of anti – streptolysin O (ASO) antibodies in human serum. ASO antibodies are found in sera of patients in response to infection with hemolytic streptococci of group A, C or G. Streptolysin O is highly antigenic therefore patients with these infections produce specific antibodies detectable by the reagent. Questions: 1. Illustrate how latex agglutination works to bind to ASO and form agglutinates 2. What is the significance of ASO? Is ASO specific to a disease? 3. What are Todd Units? Give the normal value of ASO

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