Answer: Why is the formation of 4-hydroxy-4-methyl-2-pentanone, not a major side reaction? 4-hydroxy-4-methyl-2-pentanone is not obtained as the major side product because of less reactivity of acetone as compared to anisaldehyde in which the aldehydic group is very reactive and reacts faster with carbonation than the ketonic group of acetone. The major side product may be the condensation of acetone with one molecule of anisaldehyde. The 4-hydroxy- 4-methyl-2-pentanone is formed as:

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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Why is the formation of 4-hydroxy-4-methyl-2-pentanone, not a major side reaction?
Answer:
4-hydroxy-4-methyl-2-pentanone is not obtained as the major side product because of
less reactivity of acetone as compared to anisaldehyde in which the aldehydic group is very
reactive and reacts faster with carbonation than the ketonic group of acetone. The major side
product may be the condensation of acetone with one molecule of anisaldehyde. The 4-hydroxy-
4-methyl-2-pentanone is formed as:
Transcribed Image Text:Why is the formation of 4-hydroxy-4-methyl-2-pentanone, not a major side reaction? Answer: 4-hydroxy-4-methyl-2-pentanone is not obtained as the major side product because of less reactivity of acetone as compared to anisaldehyde in which the aldehydic group is very reactive and reacts faster with carbonation than the ketonic group of acetone. The major side product may be the condensation of acetone with one molecule of anisaldehyde. The 4-hydroxy- 4-methyl-2-pentanone is formed as:
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