and its pk, is 4.8. Mark any/all that apply. HO

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The structure of a particular drug is provided below. The acid form is shown, and its pk, is 4.8. Mark
any/all that apply.
HO
O The conjugate base of this acid is charged.
O The acid form will predominate at pH 7.40.
The acid form of this drug is charged.
The conjugate base will predominate at pH 7.40.
The acid form of this drug will diffuse through the cell membrane more easily than the conjugate base will
diffuse through the cell membrane.
Transcribed Image Text:The structure of a particular drug is provided below. The acid form is shown, and its pk, is 4.8. Mark any/all that apply. HO O The conjugate base of this acid is charged. O The acid form will predominate at pH 7.40. The acid form of this drug is charged. The conjugate base will predominate at pH 7.40. The acid form of this drug will diffuse through the cell membrane more easily than the conjugate base will diffuse through the cell membrane.
Expert Solution
Step 1

The acid is a species that gives hydrogen ions in the solution. When a hydrogen ion is released by the acid, the conjugate base is formed.

 

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