An undergraduate research student wishes to create a system that mimics human blood (pH = 7.4). The student chose as the model system to use a buffer solution of sodium dihydrogen phosphate (NaH2PO4, Ka = 6.2 × 10–8) and sodium hydrogen phosphate (Na2HPO4, Ka = 4.2 × 10-13). A) Which of the components of the buffer solution is the acid? B) Using the Henderson Hasselbalch equation, calculate the mole ratio of Na2HPO4/NaH2PO4 the student needs to use. C) To approximate the human condition of blood alkalosis (where the pH of blood rises to 7.6, which is usually lethal), how much base will the student need to add to the buffer?
Ionic Equilibrium
Chemical equilibrium and ionic equilibrium are two major concepts in chemistry. Ionic equilibrium deals with the equilibrium involved in an ionization process while chemical equilibrium deals with the equilibrium during a chemical change. Ionic equilibrium is established between the ions and unionized species in a system. Understanding the concept of ionic equilibrium is very important to answer the questions related to certain chemical reactions in chemistry.
Arrhenius Acid
Arrhenius acid act as a good electrolyte as it dissociates to its respective ions in the aqueous solutions. Keeping it similar to the general acid properties, Arrhenius acid also neutralizes bases and turns litmus paper into red.
Bronsted Lowry Base In Inorganic Chemistry
Bronsted-Lowry base in inorganic chemistry is any chemical substance that can accept a proton from the other chemical substance it is reacting with.
An undergraduate research student wishes to create a system that mimics human blood (pH = 7.4). The student chose as the model system to use a buffer solution of sodium dihydrogen phosphate (NaH2PO4, Ka = 6.2 × 10–8) and sodium hydrogen phosphate (Na2HPO4, Ka = 4.2 × 10-13).
A) Which of the components of the buffer solution is the acid?
B) Using the Henderson Hasselbalch equation, calculate the mole ratio of Na2HPO4/NaH2PO4 the student needs to use.
C) To approximate the human condition of blood alkalosis (where the pH of blood rises to 7.6, which is usually lethal), how much base will the student need to add to the buffer?
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