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An inversion heterozygote has the following inverted chromosome: Centromere A B CD JI HGF E¸ KL M Inverted region What would be the products if a crossover occurred between genes H and I on the inverted chromosome and a normal chromosome?

An inversion heterozygote has the following inverted chromosome: Centromere A B CD JI HGF E¸ KL M Inverted region What would be the products if a crossover occurred between genes H and I on the inverted chromosome and a normal chromosome?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
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### Chromosomal Inversion in Heterozygotes This diagram illustrates an inverted chromosome in an inversion heterozygote. The chromosome is shown with various gene loci labeled from A to M. The chromosomal structure includes: - **Centromere**: Highlighted in yellow, this is the part of the chromosome where the two chromatids are joined. - **Inverted Region**: The section of the chromosome where the order of genes is reversed. In this case, the inversion affects the sequence CD through KL: - Normal order: C, D, E, F, G, H, I, J, K, L - Inverted order: CD, JI, HGF, E, KL **Challenge Discussion**: The diagram poses a question regarding the genetic consequences of crossover events. Specifically, it asks what products would result if a crossover occurred between genes **H** and **I** within the inverted region and a corresponding segment on a normal chromosome. Understanding these concepts is crucial in genetics, as inversions can lead to recombination suppression and affect genetic diversity. ### Key Points: - **Inversion Heterozygote**: An organism with one normal and one inverted chromosome. - **Crossover**: The exchange of genetic material between homologous chromosomes during meiosis. - **Genetic Consequence**: The crossing over between the inverted and normal chromosome can lead to duplications or deletions in the resultant gametes.
Transcribed Image Text:### Chromosomal Inversion in Heterozygotes This diagram illustrates an inverted chromosome in an inversion heterozygote. The chromosome is shown with various gene loci labeled from A to M. The chromosomal structure includes: - **Centromere**: Highlighted in yellow, this is the part of the chromosome where the two chromatids are joined. - **Inverted Region**: The section of the chromosome where the order of genes is reversed. In this case, the inversion affects the sequence CD through KL: - Normal order: C, D, E, F, G, H, I, J, K, L - Inverted order: CD, JI, HGF, E, KL **Challenge Discussion**: The diagram poses a question regarding the genetic consequences of crossover events. Specifically, it asks what products would result if a crossover occurred between genes **H** and **I** within the inverted region and a corresponding segment on a normal chromosome. Understanding these concepts is crucial in genetics, as inversions can lead to recombination suppression and affect genetic diversity. ### Key Points: - **Inversion Heterozygote**: An organism with one normal and one inverted chromosome. - **Crossover**: The exchange of genetic material between homologous chromosomes during meiosis. - **Genetic Consequence**: The crossing over between the inverted and normal chromosome can lead to duplications or deletions in the resultant gametes.
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