An influx of positive sodium ions causes opening of the activation gates of voltage regulated sodium channels resulting in a further influx of positive sodium ions, and thus the initial stages of an action potential are regulated by ______ feedback.

Human Anatomy & Physiology (11th Edition)
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An influx of positive sodium ions causes opening of the activation gates of voltage regulated sodium channels resulting in a further influx of positive sodium ions, and thus the initial stages of an action potential are regulated by ______ feedback.

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VOLTAGE GATED SODIUM CHANNELS

These are integral membrane proteins that change conformation in response to depolarization of the membrane potential.

Upon depolarization, they open transmembrane pore, and conduct sodium ions inward to initiate and propagate action potentials 

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