An infant was admitted to hospital for failure to thrive. It was discovered that theinfant lacks the enzyme to metabolize long chain fatty acids, the major fuel in mostmammals. Treatment included a diet rich in very short chain fatty acids, such ascaproic acid (which is high in goat's milk and olive oil). How much ATP would youexpect to gain from the complete oxidation of one molecule of caproic acid. (Caproicacid is a saturated fatty acid with 6 carbons).A) 36B) 38C) 40OD) 42

Saturated fatty acids undergo beta oxidation in the mitochondria. A fatty acids with 'n' carbons…

Answered: An infant was admitted to hospital for…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Similar questions

Fatty acid oxidation for energy yield occurs in the mitochondrial matrix, and for palmitate as one example, generates [FADN2, NADH, and Acetyle-CoA or FADH, GTP, and NADPH] , all of which can be converted to ATP (108 of them to be exact) via oxidative phosphorylation. This is a [greater or smaller] yield of ATP per carbon atom compared to glucose. Ketogenesis is a process where acetyl-CoA (including that from breakdown of fatty acids) is converted to ketone bodies under conditions where carbohydrates are [in excess or liminting] . Acetoacetate and D-beta-hydroxybutyrate are delivered from liver to the blood stream where they provide energy for [cardiac and skeletal muscle as well as brain or synthesis of glycogen] . [Insulin or glucagon] promotes ketogenesis by stimulating fatty acid export from adipose tissue.
Fill in the blanks below (input numbers only!) about the metabolism of hexanoic acid, a fatty acid that is one of the components of vanilla, and whose formula is CH3(CH2)4COOH: First, the fatty acid is activated by attaching CoA, which costs ATP molecules. The fatty acid is then broken down through a beta-oxidation spiral, to make acetyl CoA molecules. This will require "turns" of the beta-oxidation process. Since each turn of the cycle yields ATP molecules, and each acetyl COA will yield ATP molecules by going through the rest of its metabolism, the net ATP molecules produced from one molecule of this fatty acid will be
Complete oxidation of a triacylglycerol molecule yields about how many atp molecules ?
One condition is ketoacidosis (low blood pH) which is a potentially life-threatening state, most commonly experienced by diabetics. Ketoacidosis, however, is not typically an issue for healthy people who are following a ketogenic diet. What is the difference between ketoacidosis and ketosis? Why do diabetics sometimes develop ketoacidosis, while healthy people rarely do? Healthy people are well equipped to survive on a ketogenic diet. Why is it important that humans evolved to have the ability to survive without carbohydrate nutrients?
Lactic acid is a biproduct formed at the end of anaerobic respiration. This molecule is dangerous to cells of the body if it builds up too much. Despite this, the formation of lactic acid is very important. Explain why the process of anaerobic respiration is so important (providing reference to glycolysis, the role of coenzymes, and ATP formation).
Years ago there was interest in using uncouplers such as dinitrophenol as weight control agents. Presumably, fat could be oxidized without concomitant ATP synthesis for re-formation of fat or carbohydrate. Why was this a bad idea?
What impact would a rise in intramitochondrial oxaloacetate levels have on fatty acid synthesis? Justify your response briefly.
Pyruvate dehydrogenase deficiency is a fatal disease usually diagnosed in children. Symptoms include severe neurological damage. Elevated blood levels of lactate, pyruvate, and alanine are also seen. Explain how the deficiency of pyruvate dehydrogenase causes these elevated values.

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