An anti-enzyme drug Gordox is extracted from the pancreas of cattle and is used in the treatment of pancreatitis. Suggest the possible mechanism of action of Gordox. Pancreatitis develops as a result of premature activation of pancreatic peptidases. This may lead to the transport of trypsin into the blood due to pancreatic cells destruction. Gordox is an inhibitor of trypsin, so it inhibits the action of the enzyme on plasma proteins. Pancreatitis develops as a result of disrupted zymogen activation. Gordox is an inhibitor of trypsinogen, so it inhibits the action of zymogen on the pancreas. Pancreatitis develops as a result of a disorder in lipid digestion. Gordox

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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An anti-enzyme drug Gordox is extracted from the pancreas of
cattle and is used in the treatment of pancreatitis. Suggest the
possible mechanism of action of Gordox.
Pancreatitis develops as a result of premature activation of pancreatic
peptidases. This may lead to the transport of trypsin into the blood due
to pancreatic cells destruction. Gordox is an inhibitor of trypsin, so it
inhibits the action of the enzyme on plasma proteins.
Pancreatitis develops as a result of disrupted zymogen activation.
Gordox is an inhibitor of trypsinogen, so it inhibits the action of
zymogen on the pancreas.
Pancreatitis develops as a result of a disorder in lipid digestion. Gordox
is an inhibitor of cholecystokinin, so it inhibits the action on the
pancreas.
Pancreatitis develops as a result of premature activation of pancreatic
peptidases. Gordox is an inhibitor of trypsin, so it does not allow
trypsin to move into blood.
Pancreatitis develops as a result of trypsin exit into the blood. Gordox
is an inhibitor of trypsin, so it inhibits the activation of the enzyme.
Transcribed Image Text:An anti-enzyme drug Gordox is extracted from the pancreas of cattle and is used in the treatment of pancreatitis. Suggest the possible mechanism of action of Gordox. Pancreatitis develops as a result of premature activation of pancreatic peptidases. This may lead to the transport of trypsin into the blood due to pancreatic cells destruction. Gordox is an inhibitor of trypsin, so it inhibits the action of the enzyme on plasma proteins. Pancreatitis develops as a result of disrupted zymogen activation. Gordox is an inhibitor of trypsinogen, so it inhibits the action of zymogen on the pancreas. Pancreatitis develops as a result of a disorder in lipid digestion. Gordox is an inhibitor of cholecystokinin, so it inhibits the action on the pancreas. Pancreatitis develops as a result of premature activation of pancreatic peptidases. Gordox is an inhibitor of trypsin, so it does not allow trypsin to move into blood. Pancreatitis develops as a result of trypsin exit into the blood. Gordox is an inhibitor of trypsin, so it inhibits the activation of the enzyme.
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