A mixed inhibitor (sometimes called a mixed non-competitive inhibitor) of an enzyme:a decreases both Km and V-max.b increases Km and decreases V-max.c increases Km without altering V-max.d decreases Km without altering V-max.

Answered: A mixed inhibitor (sometimes called a…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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A mixed inhibitor (sometimes called a mixed non-competitive inhibitor) of an enzyme:

a		decreases both Km and V-max.
b		increases Km and decreases V-max.
c		increases Km without altering V-max.
d		decreases Km without altering V-max.

Expert Solution

Step 1

A type of inhibition where the inhibitor may bind to the enzyme irrespective of the enzyme being bound to the substrate. It is known as mixed inhibition because in this mode of enzyme inhibition the inhibition of enzyme is seen as a conceptual mixture of competitive and uncompetitive inhibition.