Adipocytes store fat in phospholipid-coated droplets in the cytosol. The protein perilipin is also associated with the surface of the lipid droplet. (a) Describe the likely structure of the perilipin protein. (b) Explain how phosphorylation of perilipin could help expose the lipids in the droplet to digestion by lipases.

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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2. Adipocytes store fat in phospholipid-coated droplets in the cytosol. The protein perilipin is also
associated with the surface of the lipid droplet. (a) Describe the likely structure of the perilipin
protein. (b) Explain how phosphorylation of perilipin could help expose the lipids in the droplet to
digestion by lipases.
Transcribed Image Text:2. Adipocytes store fat in phospholipid-coated droplets in the cytosol. The protein perilipin is also associated with the surface of the lipid droplet. (a) Describe the likely structure of the perilipin protein. (b) Explain how phosphorylation of perilipin could help expose the lipids in the droplet to digestion by lipases.
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