Adentify the expected major organic product generated from the reaction sequence shown. 1. OsO, 2. NaHSO H20 OH CH3 CH3 OH CH3 "ОН CH2OH + enantiomer + enantiomer + enantiomer %3D IV

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**Identifying the Expected Major Organic Products from Reaction Sequences**

Understanding the expected major organic product from a given reaction sequence is a fundamental skill in organic chemistry. In this exercise, we focus on the reaction sequence involving a cyclohexene derivative.

The given reaction involves:

1. **OsO₄ (Osmium tetroxide)**
2. **NaHSO₃ / H₂O (Sodium bisulfite in water)**

**Reaction Description:**

Osmium tetroxide (OsO₄) is used as a catalyst to perform the oxidation of alkenes to vicinal diols (glycols), specifically through a syn addition mechanism. This means that both hydroxyl (OH) groups are added to the same face of the alkene.

**Graphical Explanation:**

- **Starting Material:**
  - A cyclohexene derivative (a six-membered ring with one double bond).

- **Reaction Steps:**
  1. **OsO₄ → Syn addition of OH groups**
     - Osmium tetroxide adds hydroxyl groups in a syn manner, meaning on the same side of the double bond.
  2. **NaHSO₃ / H₂O → Reductive work-up**
     - Sodium bisulfite in water reduces the intermediate to produce a diol.

**Expected Products:**

- The major products are labeled as follows:
  - **I**: Cyclohexane with two OH groups added on the same side (cis) and a methyl group.
  - **II**: Another variant of cyclohexane with diols on the same side but a different methyl positioning.
  - **III**: A cyclohexane ring with a staggered arrangement of one OH group and a methyl group on the same side and another OH group on the other side.
  - **IV**: A cyclohexane ring with one OH group and one CH₂OH side chain extension.

Among these, the expected major organic product generated will be a product with both hydroxyl groups added syn to the same face of the former double bond. Hence:

**Options:**
- **A**. **I**
- **B**. **II**
- **C**. **III**
- **D**. **IV**

Upon reviewing the structures, the expected major organic product for this reaction sequence is the one where the hydroxyl groups are added syn,
Transcribed Image Text:**Identifying the Expected Major Organic Products from Reaction Sequences** Understanding the expected major organic product from a given reaction sequence is a fundamental skill in organic chemistry. In this exercise, we focus on the reaction sequence involving a cyclohexene derivative. The given reaction involves: 1. **OsO₄ (Osmium tetroxide)** 2. **NaHSO₃ / H₂O (Sodium bisulfite in water)** **Reaction Description:** Osmium tetroxide (OsO₄) is used as a catalyst to perform the oxidation of alkenes to vicinal diols (glycols), specifically through a syn addition mechanism. This means that both hydroxyl (OH) groups are added to the same face of the alkene. **Graphical Explanation:** - **Starting Material:** - A cyclohexene derivative (a six-membered ring with one double bond). - **Reaction Steps:** 1. **OsO₄ → Syn addition of OH groups** - Osmium tetroxide adds hydroxyl groups in a syn manner, meaning on the same side of the double bond. 2. **NaHSO₃ / H₂O → Reductive work-up** - Sodium bisulfite in water reduces the intermediate to produce a diol. **Expected Products:** - The major products are labeled as follows: - **I**: Cyclohexane with two OH groups added on the same side (cis) and a methyl group. - **II**: Another variant of cyclohexane with diols on the same side but a different methyl positioning. - **III**: A cyclohexane ring with a staggered arrangement of one OH group and a methyl group on the same side and another OH group on the other side. - **IV**: A cyclohexane ring with one OH group and one CH₂OH side chain extension. Among these, the expected major organic product generated will be a product with both hydroxyl groups added syn to the same face of the former double bond. Hence: **Options:** - **A**. **I** - **B**. **II** - **C**. **III** - **D**. **IV** Upon reviewing the structures, the expected major organic product for this reaction sequence is the one where the hydroxyl groups are added syn,
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