Activity C: Genetic Mutations: A mutation is a change in the normal DNA sequence of a gene. There are several types of mutations that can occur. A point mutation is when ONE nucleotide on the DNA is changed to a different nucleotide. Some other types of mutations include insertions (a nucleotide is added to the sequence), deletions (a nucleotide is removed from the sequence) and inversions (a piece of DNA is removed and flipped over and then added back into the sequence at the same spot.) 1. Transcribe and translate the "Original Gene" and four mutations of that gene in the table below. The initial location of each mutation is bolded and underlined. 2. Always transcribe the entire DNA sequence into mRNA. Label the 3' and 5' ends for both sequences. 3. When translating from mRNA protein amino acids, stop translation when you reach a stop codon, even if you have not reached the end of the mRNA sequence. End Sequence End 3' TAC TTG TCC GAT CCA ΑΤΑ CCC CGC ATC 5' Original Gene (DNA) mRNA codons Protein amino acids
Activity C: Genetic Mutations: A mutation is a change in the normal DNA sequence of a gene. There are several types of mutations that can occur. A point mutation is when ONE nucleotide on the DNA is changed to a different nucleotide. Some other types of mutations include insertions (a nucleotide is added to the sequence), deletions (a nucleotide is removed from the sequence) and inversions (a piece of DNA is removed and flipped over and then added back into the sequence at the same spot.) 1. Transcribe and translate the "Original Gene" and four mutations of that gene in the table below. The initial location of each mutation is bolded and underlined. 2. Always transcribe the entire DNA sequence into mRNA. Label the 3' and 5' ends for both sequences. 3. When translating from mRNA protein amino acids, stop translation when you reach a stop codon, even if you have not reached the end of the mRNA sequence. End Sequence End 3' TAC TTG TCC GAT CCA ΑΤΑ CCC CGC ATC 5' Original Gene (DNA) mRNA codons Protein amino acids
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:Activity C: Genetic Mutations:
A mutation is a change in the normal DNA sequence of a gene. There are several types of
mutations that can occur. A point mutation is when ONE nucleotide on the DNA is changed to a
different nucleotide.
Some other types of mutations include insertions (a nucleotide is added to the sequence),
deletions (a nucleotide is removed from the sequence) and inversions (a piece of DNA is
removed and flipped over and then added back into the sequence at the same spot.)
1. Transcribe and translate the "Original Gene" and four mutations of that gene in the
table below. The initial location of each mutation is bolded and underlined.
2. Always transcribe the entire DNA sequence into mRNA. Label the 3' and 5' ends for both
sequences.
3. When translating from mRNA protein amino acids, stop translation when you reach a
stop codon, even if you have not reached the end of the mRNA sequence.
End
End Sequence
3'
TAC TTG TCC
GAT CCA ΑΤΑ CCC CGC ATC 5'
Original Gene
(DNA)
mRNA codons
Protein amino
acids
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