Acetyl COA (ACC) is a critically important molecule in metabolic pathways. Thismolecule can be used for gluconeogenesis or fatty acid synthesis. It can alsoproceed through the TCA cycle to generate energy.Which of these molecules would be a negative allosteric regulator of ACC?A) citrateACC is allosterically regulated.B) ATPC) palmitoyl COAD) glucoseE) acetyl COA

ACC is the rate limiting enzyme of fatty acid synthesis pathway. ACC catalyzes the conversion of…

Answered: Acetyl COA (ACC) is a critically…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Isozymes: d) One way of regulating metabolic pathways is through isozymes. What is an isozyme? e) Provide a concrete example of an isozyme from carbohydrate metabolism. f) From your chosen isozyme in part b), describe how it is regulated differently in various cells.
If G6P is labeled at its C2 position, where will the label appear in the products of the pentose phosphate pathway?
Which of the following statements is INCORRECT? OA) The inhibition of phosphofructokinase leads to the inhibition of hexokinase. B) Fructose-1,6-bisphosphate activates pyruvate kinase. OC) In the liver, phosphofructokinase is activated by citrate. OD) GLUT5 transports fructose.
Name the anabolic pathway that synthesizes fatty acids.
Will an amino acid be glucogenic or ketogenic if it is catabolized to the following molecules?(a) Phosphoenolpyruvate(b) -Ketoglutarate (c) Succinyl-CoA(d) Acetyl-CoA(e) Oxaloacetate(f) Acetoacetate
Two carbon atoms are fed into the citric acid cycle as acetyl-CoA. In what form are two carbon atoms removed from the cycle?
Pyruvate carboxylase a) What is the overall function of pyruvate carboxylase? b) Describe the role of each of the four domains in pyruvate carboxylase. c) How do the four domains work together to perform the function of pyruvate carboxylase?
Name four amino acids that can be converted directly (in one step) into pyruvate or a citric acid cycle intermediate, and name the intermediate formed from each.
The effect of ATP on the allosteric enzyme PFK-1 is shown below. For a given concentration of fructose 6-phosphate, the PFK-1 activity increases with increasing concentrations of ATP, but a point is reached beyond which increasing the concentration of ATP inhibits the enzyme. (a) Explain how ATP can be both a substrate and an inhibitor of PFK-1. How is the enzyme regulated by ATP? (b) In what ways is glycolysis regulated by ATP levels? (c) The inhibition of PFK-1 by ATP is diminished when the ADP concentration is high, as shown in the illustration. How can this observation be explained? *A graph is included for this question*
Classify the following enzymes: Oxidoreductase, Hydrolase, Transferase, Lyase, Ligase, Isomerase 1. Sucrase - 2. Trypsin - 3. Catalase - 4. Aspartate aminotransferase - 5. Cellulase - 6. Ptyalin - 7. Lactase - 8. Creatinine phosphokinase - 9. 5- alpha reductase - 10. Aminopeptidase -
The citric acid cycle is shown. The methyl carbon in acetyl CoA is labeled with C14C14 (shown in red). Identify which of the carbons in each intermediate will be labeled in the first round of the cycle by selecting the indicated carbon(s). Each question has multiple options, please choose more than one. Which carbon(s) in α‑ketoglutarate will contain C14? 1 2 3 4 5 Which carbon(s) in succinyl‑CoA will contain C14? 1 2 3 4 Which carbon(s) in succinate will contain C14? 1 2 3 4 Which carbon(s) in fumarate will contain C14? 1 2 3 4 Which carbon(s) in malate will contain C14? 1 2 3 4 Which carbon(s) in oxaloacetate will contain C14? 1 2 3 4
Describe how a) Mean Arterial Pressure, b) Maximal Oxygen Consumption, and c) Blood Flow are determined using its formula. In addition, you should explain what those factors are including cardiac output, stroke volume, heart rate, resistance, a-vO2 difference, etc. Describe how many ATPs can be generated by complete cycles of beta oxidation of free fatty acid with 20 carbons. You should indicate how many cycles of beta oxidation and Krebs cycle, and total number of products as well

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