According to my digital archives, the O2 concentration of blood must drop to at least 92.0% to cause the symptoms that we observed in Xor. Assuming Xor is still taking 15.0 breaths/minute, what would the slope of the relationship between the rate of contraction by the diaphragm and the [02] in the blood of megaraffes if Xor was still taking 15.0 breaths/minute and the [02] in her blood was 92.0%? Directions: For questions 16-17, round all calculated values to the nearest tenth of a decimal place. For example, if you calculate the value as 3.821853, round to 3.8. 16. Estimate the slope of the linear relationship ([2] / (contraction/min)) between the rate of contraction by the diaphragm and the [02] in the blood of Xor if she was taking 15.0 breaths/minute and the [02] in her blood was 92.0%. Slope = 6.1 17. How much do we need to raise or lower the slope you estimated in the previous question in order to return it back to the healthy slope of 6.3% O₂ / (contraction/min)? As a note, if your answer to this question is a positive value, then you are saying you want to raise the slope by that value. Conversely, if your answer to this question is a negative value, you are saying you want to lower the slope by that value. Amount to raise or lower slope = 0.2 Good work! Now we know how the relationship between the rate of contraction by the diaphragm and the [02] in Xor's blood would change if Xor's breathing rate remained unchanged while her blood [02] dropped to 92.0% - the [02] concentration the blood must drop to in order to cause the symptoms we observed in Xor. Now we must determine how much drug we should give to Xor should her [02] be lower than normal. Because the drug alters how much air flows into the lungs each time the diaphragm contracts, the drug alters the slope of the relationship between the rate of contraction by the diaphragm and the [02] in Xor's blood. If we're going to determine how much drug we should give to Xor, we first must model the relationship between the dose of the drug and the slope of the relationship between the rate of contraction by the diaphragm and the [02] in Xor's blood. This will then allow us to determine how much of the drug to administer to return the slope of the relationship between the rate of contraction by the diaphragm and the [02] in Xor's blood back to 6.3% O2 / (contraction/min). Directions: For questions 18-19, download the "Effect of Drug on Slope" Excel file in Canvas containing the dose of the drug and the slope of the relationship between the rate of contraction by the diaphragm and the [02] in the blood (sample size = 13). Use Excel for calculations, modeling, and graphing. Round all calculated values to the nearest hundredths of a decimal place. For example, if you calculate the value as 3.821853, round to 3.82. Slope (% 02/(contraction/min)) Formatting Instructions: General Chart type: XY (Scatter) • Quick layout: Layout 1 - Scatter (you can delete the key/legend on the right if you want and the chart title) Y-axes title: "Slope (% O2/(contraction/min))"; Font size = 18 • Y-axis numbers: Font size = 14 • X-axis title: "Drug dose (g)"; Font size 18 Y-axis X-axis numbers: Font size=14 • Bounds: minimum at 6.10, maximum at 6.50 X-axis • Bounds: minimum at 3, maximum at 9 Trendline (linear model) • Line: Solid line 6.50 6.40 6.30 6.20 6.10 3 4 5 6 7 8 9 Drug dose (g) 19. Estimate the slope of the linear relationship (([02] / (contraction/min)) / g) between the dose of the drug and the slope of the relationship between the rate of contraction by the diaphragm and the [02] in the blood. Slope 0.048 > 0.05