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- 151 Phenylketonuria (PKU) is a disorder caused by a recessive allele. Two carrier individuals have progeny. Answer the following questions in order and show solutions whenever relevant. Indicate the gene notation. Derive the expected genotypic and phenotypic ratios.tate. edu/d21/le/content/5003190/viewContent/44248878/View 10. The genes Stubble (Sb), Lyra (Ly), and bright (br) are all linked on chromosome 3 in Drosophila fruit flies. An organism that was heterozygous for all three genes was mated to an organism that was homozygous recessive for all three. The following phenotypes were seen in the offspring: All wild-type 422 Lyra and Stubble 4. Stubble and bright 16 Lyrà and bright 75 Lyra only 18 Stubble only 59 Bright only Lyra, Stubble, and bright 404. f. What are the alleles in the parental gametes?CIUSS O An organism has the genotype a g*/a"g*; qf"/q+f*;r+h+/rth*. Indicate the correct genes/ alleles at all the positions numbered 1-12 in the image below such that the diagram accurately represents the genotype of this organism. Note: assume the first chromosome in each pair shown in the genotype is the top chromosome shown in the diagram. 1 i 2: a gene g gene 6. q gene fgene 7 8. | 10 r gene h gene 12 Only place the genes/ alleles you need. You will not need them all. You may need to use some more than once. • gene / allele 1 a- ; gene / allele 2 g+ ; gene / allele 3 a- gene/allele 4 g++ • gene / allele 5 q- ; gene / allele 6 f- gene / allele 7 q+; gene / allele 8 f- gene / allele 9 r+; gene / allele 10 h+ gene / allele 11 r+ gene / allele 12 h+ a+ a- f+ f- g+ g- h+ h- q+ q- r+ r- 2.
- Neurospora of genotype a + c are crossed withNeurospora of genotype + b +. (Here, + is shorthandfor the wild-type allele.) The following tetrads areobtained (note that the genotype of the four sporepairs in an ascus are listed, rather than listing alleight spores):a + c a b c + + c + b c a b + a + ca + c a b c a + c a b c a b + a b c+ b + + + + + b + + + + + + c + + ++ b + + + + a b + a + + + + c + b +137 141 26 25 2 3a. In how many cells has meiosis occurred to yieldthese data?b. Give the best genetic map to explain these results.Indicate all relevant genetic distances, both betweengenes and between each gene and the centromere.c. Diagram a meiosis that could give rise to oneof the three tetrads in the class at the far right inthe listGiven the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the phenotype of this individual be?Purple flowers are dominant to white flowers. Identify the phenotypefor the following genotype Ff, FF, ff and determine if the genotype is heterozygous or homozygous. * For each row, you should select two columns. Purple flowers White flowers Heterozygous Homozygous Ff FF ff Brown eyes are dominant to blue eyes. Identify the phenotype for the following genotype BB, Bb, bb and determine if the genotype is heterozygous or homozygous. * 口 ロ口
- Pedigree Analysis Is a Basic Method in Human Genetics Using the pedigree provided, answer the following questions. a. Is the proband male or female? b. Is the grandfather of the proband affected? c. How many siblings does the proband have, and where is he or she in the birth order?GsnKivd010j2gIRWLIZOMZZ-VibKYvBbo61ylATAQ/viewform RECOMBINATION". For numbers 7-35, reler to the given data below. Glven the following testcross data for com In whlch the genes for fine stripe (f), bronze gleurone (bz) and knotted leaf (Kn) are involved: + = wild type f fine stripe +=wild type bz = bronze gleurone +=wild type Kn knotted leaf %3D Genotype Ko f Number 451 Ko 134 97 436 bz bz bz Ko 18 119 f 24 Kn f bz 86 Total: Your answer 7-8. What would be the recombination frequency or the frequency of the recombinant type between +/Kn and +/f genes? Oa. 16% O b. 16 map units + + + + +Consider the parental cross rY x RR, where r is the trait/disease allele, and R is the wild-type allele. The mode of inheritance is sex-linked recessive. Compute the ratios (Wild-type/non-disease phenotype):(Disease phenotype) for the F1 and F2 generations. Check the syllabus to see what formats are allowable for submission (e.g., pdf, docx, etc). Note: if you use a text editor like Notepad, you must use Courier New font. Also, you must show all work, akin to the work shown in the pdf lecture. Hint: In the F1 generation, individuals can only mate with the opposite gender.
- A friend tells you that her biological father has an inherited disorder determined by a dominant allele but neither your friend nor her three siblings are affected. Is this possible? If not, why not? If so, explain how it is possible. For the toolbar, press ALT+F10 (PC) or ALT+FN+F10 (Mac). BIUS Paragraph Arial 14px A V x² X, ABC 田 田 | 国田用田 Ť {;} III !!! +)Is this karyotype male or female? What kind of error (if any) Name of syndromeThe genotype of EB27 and EB67 are unknown. Based on pedigree, what are the most likely genotype of each individual?