a. What is the 25th percentile of HDL in patients recelving the placebo? b What is median HDL. in patients receiving the new drug? c Are there any outliers in HDLin patients recein ng the new drug? Justify.

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17. A dinical trial is conducted to cvaluate the elicacy
of a new drug to increase HDL cholesterol ("good"
cholesterol) in men at high risk for cardiovasular
disease. Particiipants are randomized to receive the
new drug or placebo and followed for 12 weeks, at
which time HDL cholesterol ix measured. The data
are summarized in Figure 4-28.
1 What is the 25th percentile of HDL in patients
receiving the placebor
b What is median HDL. in patients receivıng the
new drug
c Are there any outliers in HDL in patients recen
the new drug? Justify.
ing
Transcribed Image Text:17. A dinical trial is conducted to cvaluate the elicacy of a new drug to increase HDL cholesterol ("good" cholesterol) in men at high risk for cardiovasular disease. Particiipants are randomized to receive the new drug or placebo and followed for 12 weeks, at which time HDL cholesterol ix measured. The data are summarized in Figure 4-28. 1 What is the 25th percentile of HDL in patients receiving the placebor b What is median HDL. in patients receivıng the new drug c Are there any outliers in HDL in patients recen the new drug? Justify. ing
FIGURE 4-28 HDL Cholesterol
New Drug
Placebo
30
35
40
45
50
55
Transcribed Image Text:FIGURE 4-28 HDL Cholesterol New Drug Placebo 30 35 40 45 50 55
Expert Solution
Step 1

a.

First quartile:
 
First quartile is the median of all the observations that are left to the ‘location of overall median’. It is the 25th percentile which determines the 25% of the data values lie below the first quartile. In the boxplot, the bottom line (towards left) of the box represents the first quartile.

From the boxplot of HDL cholesterol, the first quartile value for patients receiving placebo corresponds to the bottom line (towards left) of the box. The bottom line of the boxplot for placebo corresponds to the value 35. The first quartile or the 25th percentile is 35.

Thus, the 25th percentile of HDL patients receiving placebo is 35.

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