A variation of the acetamidomalonate synthesis can be used to synthesize threonine. The process involves the following steps: Ethoxide ion deprotonates diethyl acetamidomalonate, forming enolate anion 1; Enolate anion 1 makes a nucleophilic attack on acetaldehyde, forming tetrahedral intermediate 2; Protonation of the oxyanion forms alcohol 3; Acid hydrolysis yields dicarboxyamino alcohol 4; Decarboxylation leads to the final amino acid. Write out the mechanism on a separate sheet of paper, and then draw the structure of enolate anion 1.

Q: What carboxylic acid and amine are needed to synthesize the pain reliever phenacetin? Phenacetin was…

A: Phenacetin is an analgesic drug that reduces pain and fever. Furthermore, chemical name of…

Q: Propose a synthesis of the tranquilizer valnoctamide from diethyl malonate.

A: Synthesis of tranquilizer valnoctamide: In this synthesis, the first step involves diethyl malonate…

Q: Reaction of p-nitroaniline with sodium nitrite and hydrochloric acid at 0°C, followed by treatment…

A: The objective of teh question is to predict the product formed in the following reaction given.

Q: The following three derivatives of succinimide are anticonvulsants and have found use in the…

A: Starting from benzaldehyde we get phensuccimide that has a phenyl group and an H at carbon alpha to…

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A: Structure of Amobarbital is,

Q: The reaction of cyclohexanone and N,N-dimethylamine with sodium triacetoxyborohydride (NaBH(OAc)3)…

A: This is an example of reductive amination reaction in which a ketone reacts with amine in the…

Q: The carbon in glucose that determines whether it is a D or L sugar is carbon number 3 O 5

A:

Q: Amobarbital is a sedative marketed under the trade name Amytal. Propose a synthesis of amobarbital,…

A: Structure of Amobarbital is,

Q: Synthetize 3-phenyl-2-propenoic acid from benzaldehyde using whateve organic/inorganic reagents are…

A: The required compound can be prepared by using Perkin's reaction.

Q: Draw the structure for the following compounds It organic 1: 2,2 diiodo-3-pentenoic acid 2:…

A: To solve this problem we have to draw the structure of given compounds . To draw the structure we…

Q: Two reactions occur when sodium hydroxide is added to methyl salicylate. One is immediate and one…

A: This reaction is called saponification reaction. Where we produce sodium salt.

Q: H,N NH COC,H; C. C,H5. 1. C,H,O¯N * 2. H,0 9. 2) \4. C=0 O + 2C,H;OH C,H, NH C,H; COC,H, H,N…

A:

Q: Predict the products formed when cyclohexanone reacts with the following reagents. h) sodium…

A: SOLUTION: Step 1: The reaction of sodium acetylide with the cyclohexanone (ketone) is an example of…

Q: The mechanism for acidic hydrolysis of a nitrile resembles the basic hydrolysis, exceptthat the…

A: The acidic hydrolysis of benzonitrile to the benzoate ion and ammonia comprises three steps. The…

Q: A variation of the acetamidomalonate synthesis can be used to synthesize serine. The process…

A:

Q: Synthesize benzylamine from benzaldehyde

A: A question based on synthesis of benzylamine, which is to be accomplished.

Q: Which of the following statements is correct? An aldehyde can react with a secondary amine through a…

A:

Q: alai 4 ich is Ammonia Acetic acid HCI NaOH Lläs 4 * N,N-Dimethylbutylamine is Symmetrical tertiary…

A: The answer to the following questions are as follows:

Q: Following are structural formulas for amphetamine and methamphetamine. H NH, CH3 (a) (b) Amphetamine…

A: (a) Treatment of 1-phenylpropan-2-one with ammonia in the presence of sodium cyanoborohydride gives…

Q: When 4-hydroxybutanoic acid is treated with an acid catalyst, it forms a lactone (a  cyclic ester).…

A: 4-hydroxybutanoic acid is treated with an acid catalyst, it forms a lactone.

Q: Propose mechanisms for the nucleophilic acyl substitutions to form ethyl benzoate…

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Q: Reductive amination requires a hydrogen on the carbonyl carbon to proceed BECAUSE Reductive…

A: Reductive amination reaction is a “carbonyl condensation reaction” is one in which two carbonyl‑…

Q: How imines and enamines are converted back to carbonyl compounds by hydrolysis with mild acid ?

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Q: Propose a mechanism for the reaction of bisphenol A with phosgene.

A: Structure of bisphenol A and phosgene are as follows.

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Q: complete the reaction and draw: N-methylethanamine is treated with acetophenone and the resulting…

A: The reaction proceeds by protonation followed by nucleophilic attack of amine on carbonyl carbon.

Q: The following product can be made from the reductive amination of which combination of compounds?…

A:

Q: H3C ОН O NH₂ Br2, NaOHaq H3C О н + CO2 + NH3

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Q: Carboxylic acid is treated with an alcohol and an acid catalyst, an ester is formed and this…

A: Esterification is a general name for the reaction of synthesis of ester. Typically an acid and…

Types of Polymers on the basis of Method of Preparation