A study of breast cancer in postmenopausal women included 500 cases of invasive breast cancer and 500 subjects without breast cancer matched to the cases by age and location of residence. The following data were collected for these subjects about their use of estrogen replacement therapy (ERT). Based on these data, answer the following questions.| STATUS | CASES | CONTROLS ||-------------------------------|-------|----------|| Estrogen Replacement Therapy | 250 | 100 || No ERT | 250 | 400 |4. What is the odds of using ERT among the controls?- 400/650- 100/300- 100/500- 100/400

Odds Ratio: The measure of association between the exposure and an outcome in a population is…

Answered: A study of breast cancer in…

MATLAB: An Introduction with Applications

6th Edition

ISBN:9781119256830

Author:Amos Gilat

Publisher:Amos Gilat

Chapter1: Starting With Matlab

Section: Chapter Questions

Problem 1P

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An epidemiologist found five cases of “big toe cancer” in the Yukon Territory. Because there were only a few cases, the epidemiologist decided to conduct a matched case-control study to determine whether shoe size larger than 9 is a risk factor for big toe cancer. Cases were individually matched to one control for daily activity, history of athlete’s foot, and history of ingrown toenails. The following data were gathered: Shoe size > 9 Pair Case Control 1 Yes No 2 No No 3 No Yes 4 Yes Yes 5 No Yes Compute the proper measure of association. Interpret your results. If you were to investigate a rare cancer in Lynchburg, where might you look for data? What would be necessary legally and ethically to be able to utilize this data set(s)? Submit your thread by 11:59 p.m. (ET) on Thursday of Module/Week 3, and submit your replies by 11:59 p.m. (ET) on Sunday of the same module/week. 1
What is the distinguishing feature of a case-control study such as this? An epidemiologist performed a case-control study examining whether tobacco use was associated with oral cancer. The investigator recruited a random sample of 75 adults with oral cancer and 72 adults without oral cancer. Participants were interviewed and asked about their history of tobacco use. O Exposure status was assessed, and then the participants were followed up over time to see who developed the outcome. O The exposure and outcome were measured at the same time, so temporality cannot be established. O Participants were selected based on disease status, and then exposure status was assessed from the past. O The investigator randomized participants into exposure groups and then followed them to see who developed the outcome.
A case-control study is conducted to assess the relationship between heavy alcohol use during the first trimester of pregnancy and miscarriage. Fifty women who suffered miscarriage are enrolled along with 50 who delivered full term. Each participant’s use of alcohol during pregnancy is ascertained. Heavy drinking is defined as 4 or more drinks on one occasion. The data are shown below. Miscarriage Delivered Full Term Heavy Alcohol Use 14 4 No Heavy Alcohol Use 36 46 Compute the odds of miscarriage among women with heavy alcohol use in pregnancy.
The following table represents the results of the study which compares effects of regular coffee vs decaffeinated coffee. The outcome is a development of headache. Regular coffee Headaches 17 Decaffeinated coffee 9 Total 26 No headaches 51 55 106 Which of the values best represents the risk difference(RD) in this study?
The Bureau of Labor Statistics reports that the official unemployment rate for Black people was 10.4% and 4.7% for White people in February 2015. Select all correct answers for this question. O The samples of white and black people are independent. The explanatory variable is the unemployment rate. The response variable is the unemployment rate. The response variable is race.
A researcher gathered a sample of participants who volunteered for a studying of phobias. She measured anxiety level of participants as they viewed photos of spiders and again when they viewed puppies. Which statistical test is appropriate for this study and why?
The Behavioral Risk Factor Surveillance System is an ongoing health survey system that tracks health conditions and risk behaviors in the United States. In one of their studies, a random sample of 8,866 adults answered the question "Do you consume five or more servings of fruits and vegetables per day?" The data are summarized by response and by age-group in the frequency table below. Age-Group (years) Yes No 18-34 231 35-54 669 55 or older Total 1,291 2,191 741 2,242 3,692 6,675 Total 972 2,911 4,983 8,866 Do the data provide convincing statistical evidence that there is an association between age-group and whether or not a person consumes five or more servings of fruits and vegetables per day for adults in the United States? The value of the test statistic is 83.663. Use a 0.05 level of significance to test the hypothesis. The critical value is 5.991. What is the expected number of 19-34-year-olds who say that they consume five or more servings of fruits and vegetables per day? Among…
A food-frequency questionnaire is used to measure dietary intake. The respondent specifies the number of servings of various food items they consumed over the previous week. The dietary cholesterol is then quantified for each respondent. The researchers were interested in assessing if there was an association between dietary cholesterol intake and high blood pressure. In a large sample of individuals who had completed the questionnaire, 250 persons with a high dietary cholesterol intake (greater than 300 mg /day) were selected and 250 persons with a low dietary cholesterol intake (less than 300 mg/day) were selected. The 500 selected participants had their medical history taken and were classified as having normal or high blood pressure. The data are given here. Dietary Cholesterol Blood Pressure Total High Low High 159 91 250 Low 78 172 250 Total 237 263 500 Test 2: two-tailed test for comparing two independent proportions Clearly state…
A case-control study is conducted to assess the relationship between heavy alcohol use during the first trimester of pregnancy and miscarriage. Fifty women who suffered miscarriage are enrolled along with 50 who delivered full term. Each participant’s use of alcohol during pregnancy is ascertained. Heavy drinking is defined as 4 or more drinks on one occasion. The data are shown below. Miscarriage Delivered Full Term Heavy Alcohol Use 14 4 No Heavy Alcohol Use 36 46 a. Compute the odds of miscarriage in women with heavy alcohol use in pregnancy. b. Compute the odds of miscarriage in women with no heavy alcohol use in pregnancy. c. Compute is the odds ratio for miscarriage as a function of heavy alcohol use.
You conducted a study to assess the effect of smoking on systolic blood pressure. The results showed that there was a significant association between the two variables, with an odds ratio of 1.5. Explain this finding to someone who has no background in epidemiologic research.
Acne is a common skin disease that affects most adolescents and can continue into adulthood. A study compared the effectiveness of three acne treatments and a placebo, all in gel form, applied twice daily for 12 weeks. The study's 517 teenage volunteers were randomly assigned to one of the four treatments. Success was assessed as clear or almost clear skin at the end of the 12 week period. The results of the study can be seen in the table below. Using the appropriate statistical test, determine if there is significant evidence that the four treatments perform differently. If so, how do they compare.
Suppose an investigator has studied the possible association between the use of a weight-loss drug and a rare central nervous system (CNS) disorder. He samples from a group of volunteers with and without the disorder, and records whether they have used the weight-loss drug. The data are summarized in the attached table: What is the estimated the odds ratio for the presence of a CNS disorder, comparing people who have used the weight-loss drug to those who have not? What test would you use to evaluate the null hypothesis of no association between weight-loss drug use and presence of a CNS disorder?

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