A study of breast cancer in postmenopausal women included 500 cases of invasive breast cancer an 500 subjects without breast cancer matched to the cases by age and location of residence. The following data were collected for these subjects about their use of estrogen replacement therapy (ERT). Based on these data, answer the following questions. STATUS CASES CONTROLS Estrogen Replacement Therapy 250 100 No ERT 250 400

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**Breast Cancer Study in Postmenopausal Women**

A study was conducted on postmenopausal women to investigate the potential link between estrogen replacement therapy (ERT) and invasive breast cancer. This study included 500 women diagnosed with invasive breast cancer (cases) and 500 women without breast cancer (controls), matched by age and residence location. The subjects were categorized based on their use of ERT. The data collected is summarized below:

| **Status**                       | **Cases** | **Controls** |
|--------------------------------|----------|-------------|
| Estrogen Replacement Therapy   | 250      | 100         |
| No ERT                         | 250      | 400         |

**Question:**
What is the parameter of interest to be estimated in the study?

- Difference in Prevalence
- Odds Ratio
- Relative Risk
- Difference in Incidence

The parameter of interest in this study is most likely the Odds Ratio, as it compares the odds of ERT usage between the cases and controls.
Transcribed Image Text:**Breast Cancer Study in Postmenopausal Women** A study was conducted on postmenopausal women to investigate the potential link between estrogen replacement therapy (ERT) and invasive breast cancer. This study included 500 women diagnosed with invasive breast cancer (cases) and 500 women without breast cancer (controls), matched by age and residence location. The subjects were categorized based on their use of ERT. The data collected is summarized below: | **Status** | **Cases** | **Controls** | |--------------------------------|----------|-------------| | Estrogen Replacement Therapy | 250 | 100 | | No ERT | 250 | 400 | **Question:** What is the parameter of interest to be estimated in the study? - Difference in Prevalence - Odds Ratio - Relative Risk - Difference in Incidence The parameter of interest in this study is most likely the Odds Ratio, as it compares the odds of ERT usage between the cases and controls.
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