A student wanted to know whether the greater proximity of the ucleophile to the C-2 carbon in the transition state is what causes the 1,2-addition product to be formed faster when 1,3-butadiene reacts with HCl. Therefore, she decided to investigate the reaction of 2-methyl-1,3-cyclohexadiene with HCl.Her friend told her that she should use 1-methyl-1,3-cyclohexadiene instead. Should she follow her friend’s advice?

Q: When ethyl bromide is added to potassium tert-butoxide, the product is ethyl tert-butyl ether. What…

A: Reaction is:

Q: Choose all the nucleophiles OH-     H3O+     NH4+     CH3OH     (CH3)3CLi     CH3CH2CH3     NaNH2…

A: Nucleophile :-A chemical species which have free pair of electronsor can denote pair of electrons…

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Q: Draw the structure (including stereochemistry) of an alkyl chloride that forms each alkene as the…

A: Both ‘H’ and ‘Br’ group should be trans to each other. Thus the alkyl halides needed for the…

Q: Acyl transfer (nucleophilic substitution at carbonyl) reactions proceed in two stages via a…

A: Under acidic condition the carbonyl group gets activated by protonation followed by attack by the…

Q: Explain why a methoxy group (CH3O) increases the rate of electrophilic aromatic substitution, but…

A: Methoxy group (CH3O) increases the rate of the rate of electrophilic aromatic substitution reaction,…

Q: The compound below can be prepared with an alkyl iodide and a suitable nucleophile. Identify the…

A:

Q: Give the products of the following substitution reactions. For every reaction, show electron pairs…

A: Given : We have to make the substituted products for the given reactions.

Q: Rank the following in terms of reactivity towards a nucleophile (1 = least reactive and 4 = most…

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Q: 4. S'Na* acetone 5. Br CH3C=CLi* DMSO

A: 4. Secondary alkyl iodide and strong nucleophile prefers sn2 reaction. 5. Primary alkyl bromide and…

Q: Why do cis-1-bromo-2-ethylcyclohexane and trans-1-bromo-2-ethylcyclohexane form different major…

A:

Q: Good nucleophiles that are weak bases favor substitution overelimination. Explain this ?

A: Good nucleophiles are weak bases which favor substitution often.

Q: Why does increasing alkyl substitution increase the rate of an E2 reaction?

A: The increase in E2 reaction rate with increasing alkyl substitution can be rationalized in terms of…

Q: Br Br

A:

Q: The reaction of an amine with an alkyl halide gives an ammonium salt. The rate of this SN2 reaction…

A:

Q: 1.) 2.) Br

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Q: Explain why quinuclidine is a much more reactive nucleophile than triethylamine, even though both…

A:

Q: What is the IUPAC nomenclature of the main product formed during this mechanism?

A: 4 bromo octane will be the major product in this reaction as it is formed through a more stable…

Q: A в C

A: In a nucleophilic addition-elimination reaction, the reactivity of different compounds can vary…

Q: Explain why quinuclidine is a much more reactive nucleophile thantriethylamine, even though both…

A: The chemical species that donates a pair of electron to form a chemical bond is called a…

Q: Choose the reagents suitable for the following transformations.

A: Option B ) is correct

Q: rank these from least to most reactive in nucleophilic acyl substitution with a nucleophile…

A: CH3COOC2H5CH3COONaCH3COClCH3CONH2

Q: which will proceed more easily at room temperature the bromination of cyclohexene or the bromination…

A: Given compound:- 1)Cyclohexene 2) Benzene

Q: Which of these nucleophiles would be the best for converting a tertiary alkyl halide into an…

A: Nucleophilic substitution is that type of reaction in which electron rich nucleophile attacks the…

Q: Which is the best set of reagents to carry out this transformation? CH3 H;C CH3 HC О 1. ВНЗ 2.…

A: In this question we have to complete the reaction by providing the good reagent.

Q: Which solvent would make the bromination through electrophilic aromatic substitution faster?…

A: Generally bromination through electrophilic aromatic substitution is more efficient in polar…

Q: Which nucleophile would prefer simple addition over conjugate addition? CH3MgBr NaCN CH3CH2NH2…

A: Given that, the given nucleophiles are CH3MgBr NaCN CH3CH2NH2 (CH3CH2)2CuLi We have to tell among…

Q: The following reaction involves two sequential Heck reactions. Draw structural formu- las for each…

A: Given reaction,

Q: Define the Stereochemistry of the E2 Reaction ?

A: A chemical reaction is symbolic representation of the conversion of substances to new substances. In…

Q: This reaction is an example of conjugate addition of a nucleophile to an a,ß-unsaturated carbonyl.…

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Q: During a Friedel-Crafts alkylation, the order in which the reagents are mixed is important.…

A: The correct answer about Fridel crafts reaction is given below

Q: A student wanted to know whether the greater proximity of the nucleophile to the C-2 carbon in the…

A: The reaction of HCl with 2-methyl-1,3-cyclohexadiene will form 1,2-addition product and 1,4-addition…

Q: For each compound predict if it's positive or negative for AgNO3/EtOH Test (SN1), propose 1 sentence…

A: