A physician is treating two different patients. Patient A is being treated with gentamicin (therapeutic index of 3) while patient B is being treated with benzyl penicillin (therapeutic index greater than 100). The initial treatments for both of these patients have failed. Which patient can SAFELY receive a dose increase? A. Patient A B. Patient B

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Substance Abuse

Substance abuse refers to the use of illegal drugs in excessive quantities, as well as the misuse of legal substances such as prescription or over-the-counter pharmaceuticals or alcohol for purposes other than those intended. Drug addiction, also known as substance use disorder, is a disease that affects the brain and behavior of a person. It leads to a failure to control the use of any drug or prescription, legal or illegal.