Answer the following questions using data from the figure above. a. What is the overall treatment effect? b. Provide a written interpretation of the treatment effect and 95% confidence interval. Support you answer with data from the table above. c. Would you implement the intervention (YES or NO)? Provide rationale for your answer considering the spheres of the EIDM model.
Answer the following questions using data from the figure above. a. What is the overall treatment effect? b. Provide a written interpretation of the treatment effect and 95% confidence interval. Support you answer with data from the table above. c. Would you implement the intervention (YES or NO)? Provide rationale for your answer considering the spheres of the EIDM model.
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Author:Elaine N. Marieb, Katja N. Hoehn
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Answer the following questions using data from the figure above.
a. What is the overall treatment effect?
b. Provide a written interpretation of the treatment effect and 95% confidence interval. Support you answer with data from the table above.
c. Would you implement the intervention (YES or NO)? Provide rationale for your answer considering the spheres of the EIDM model.
![Question based on the systematic review summarized below.
Purpose: To assess the effectiveness of cranberry products compared to no
treatment/placebo in preventing urinary tract infections (UTIS) in susceptible
populations.
Studies eligible for inclusion in the review: Participants included women with a
history of recurrent lower UTIS (more than 2 episodes in the previous 12 months).
All randomized controlled trials of cranberry juice (or derivatives) versus placebo, no
treatment or any other treatment were included. All included trials used random
allocation to treatment and control groups.
The primary outcome in the systematic review was number of UTIS (confirmed by a
catheter specimen of urine, midstream specimen of urine, or 'clean catch' specimen).
The meta-analysis for the systematic review is found in the table below.
Study or subgroup
Cranber-
ry product
Place-
Risk Ratio
Weight
Risk Ratio
bo/control
n/N
M-H, Random, 95% CI
M-H, Random, 95% CI
n/N
1.1.1 Women with recurrent UTIS
Barbosa-Cesnik 2011
31/155
23/164
8.74%
1.43(0.87,2.331
Kontiokari 2001
12/46
19/45
6.96%
0.62(0.34,1.12)
Sengupta 2011
2/21
4/13
1.46%
0.31|0.07,1.46]
Stothers 2002
19/100
16/50
7.32%
0.59(0.34,1.05]
Subtotal (95% CI)
322
272
24.48%
0.74[0.42,1.31)
Total events: 64 (Cranberry product), 62 (Placebo/control)
Heterogeneity: Tau-0.2; Chi-8.5, df-3(P-0.04); P=64.7%
Test for overall effect: Z-1.03(P-0.3)
0.1
100 Less with placebo/control
10
Less with cranberry 0.01](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F2d50d4df-b880-440f-8f70-9d00f72d825e%2F0ae5b22a-48e3-413e-a0c9-3c938e002ba8%2Fqnxehcv_processed.jpeg&w=3840&q=75)
Transcribed Image Text:Question based on the systematic review summarized below.
Purpose: To assess the effectiveness of cranberry products compared to no
treatment/placebo in preventing urinary tract infections (UTIS) in susceptible
populations.
Studies eligible for inclusion in the review: Participants included women with a
history of recurrent lower UTIS (more than 2 episodes in the previous 12 months).
All randomized controlled trials of cranberry juice (or derivatives) versus placebo, no
treatment or any other treatment were included. All included trials used random
allocation to treatment and control groups.
The primary outcome in the systematic review was number of UTIS (confirmed by a
catheter specimen of urine, midstream specimen of urine, or 'clean catch' specimen).
The meta-analysis for the systematic review is found in the table below.
Study or subgroup
Cranber-
ry product
Place-
Risk Ratio
Weight
Risk Ratio
bo/control
n/N
M-H, Random, 95% CI
M-H, Random, 95% CI
n/N
1.1.1 Women with recurrent UTIS
Barbosa-Cesnik 2011
31/155
23/164
8.74%
1.43(0.87,2.331
Kontiokari 2001
12/46
19/45
6.96%
0.62(0.34,1.12)
Sengupta 2011
2/21
4/13
1.46%
0.31|0.07,1.46]
Stothers 2002
19/100
16/50
7.32%
0.59(0.34,1.05]
Subtotal (95% CI)
322
272
24.48%
0.74[0.42,1.31)
Total events: 64 (Cranberry product), 62 (Placebo/control)
Heterogeneity: Tau-0.2; Chi-8.5, df-3(P-0.04); P=64.7%
Test for overall effect: Z-1.03(P-0.3)
0.1
100 Less with placebo/control
10
Less with cranberry 0.01
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