A pharmaceutical company wants to concentrate an Ivermectin solution to 50%. It was fed at a relatively low viscosity at 2.5 kg/s 15% wt. basis. The feed temperature is 25°C and the specific heat capacity is kept constant at 4 kJ/kg-K. There are possible combinations of the operation that can be conducted and the table below shows the options of the company.   For Double-Effect Operation, Feed-Forward, A1=A2 Steam Conditions Last Effect Vapor Chest Conditions U (kW/m2K) Saturated at 18 psia Saturated at 18.91 psi vacuum Effect 1: 4.5, Effect 2: 3.2 18 psia, 390 K 17.91 psi vacuum, 375 K Effect 1: 4.0, Effect 2: 3.0   The company rates the operation based on the net heat requirement and the steam economy according to this formula: Rating =S.E. (50) +50 ( 1- q, kW/1000 kW) The higher the rating, the better option the design becomes. What can be the best recommendation for the different combinations of the conditions presented above?

Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
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A pharmaceutical company wants to concentrate an Ivermectin solution to 50%. It was fed at a relatively low viscosity at 2.5 kg/s 15% wt. basis. The feed temperature is 25°C and the specific heat capacity is kept constant at 4 kJ/kg-K. There are possible combinations of the operation that can be conducted and the table below shows the options of the company.

 

For Double-Effect Operation, Feed-Forward, A1=A2

Steam Conditions

Last Effect Vapor Chest Conditions

U (kW/m2K)

Saturated at 18 psia

Saturated at 18.91 psi vacuum

Effect 1: 4.5, Effect 2: 3.2

18 psia, 390 K

17.91 psi vacuum, 375 K

Effect 1: 4.0, Effect 2: 3.0

 

The company rates the operation based on the net heat requirement and the steam economy according to this formula:

Rating =S.E. (50) +50 ( 1- q, kW/1000 kW)

The higher the rating, the better option the design becomes. What can be the best recommendation for the different combinations of the conditions presented above?

 

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