A pentapeptide was found to increase the rate of hydrolysis of fats in the adipose tissues to provide fatty acids as source of energy. The amino acid sequence of this peptide was determined to be: ALA-ARG-LYS-MET-SER Hydrolysis of the three variants of the peptide, and analysis of their amino acid composition revealed the following changes Variants Amino Acid Replacement Peptide 1 Arg was replaced by Leu Peptide 2 Ala was replaced by Tyr Peptide 3 Arg was replaced by Glu What will be the positions of these variant peptides compared with the normal peptide in an electrophoretic run at pH 7.0?

Q: ADH1A alcohol dehydrogenase 1A (class I) Describe a way in which the gene can be manipulated to…

A: * The gene ADH1A alcohol dehydrogenase  gene encodes a member of the alcohol dehydrogenase family.…

Q: A solution of peptide of unknown sequence was divided into 2 samples. One sample was tre with…

A: Site specific proteases are enzymes that cleaves polypeptide chains only at specific sites i.e. at…

Q: How is the peptide shown named (give each 3-letter name for the amino acids present)? Whichamino…

A: The peptide is made up of amino acid. The sequence of amino acid in this peptide is N - Val-Phe-Trp-…

Q: Translate the given amino acid sequence into one-letter code.…

A: Genetic codons are long enough to be taken in account in research purposes. So as for such, some…

Q: In a folded protein, Glu116 is close in three-dimensional space to Lys224. The pKa of the carboxylic…

A: pKa is the pH at which a weak acid is 50% dissociated. Alternatively, pKa = -log Ka. In acid-base…

Q: Digestion of a peptide with trypsin generates two smaller peptide products: methionine-glycine and…

A: pepsin is a serine protease that cleaves the bond present in the C-terminal of amino acids Lysine…

Q: Trypsin digestion of the peptide sequence M3-E4-R5-P6-F7-Hg-Ag-10-A11-R12-T13-Y14- G15-P16 results…

A:

Q: A peptide with 19 amino acid residues was digested with trypsin and generated the following…

A: The one letter code for different amino acids are :-  G - glycine I - isoleucine  R - arginine  S -…

Q: The 20 different amino acids in the protein are normally coded by ------ nucleotides. * 60 61 62 63

A: Nucleotides are building blocks of nucleic acids. Three mRNA nucleotides present together are known…

Q: Consider the following coding 71 nucleotide DNA template sequence (It does not contain a…

A: In cell protein formed according to the sequence on mRNA. mRNA is formed from DNA sequence by the…

Q: Why would the mutation Ile -> Asp be likely to destabilize a protein? Why would the mutation Ile…

A: Mutations in proteins' amino acid sequences can have an impact on their stability. Long sequences of…

Q: Consider the following peptide sequence: Met-Ser-Val-Thr-Ile-Lys-Ala-Cys-Leu-Ser-lle-Tyr-Phe-Ser…

A: Structure of a protein or a peptide is described in four levels: primary, secondary, tertiary and…

Q: The following questions refer to the peptide with a sequence of: Asp-Ser-Lys-Asn-Glu a) Would you…

A: Amino acids are biomolecules that have an amino group and a carboxyl group linked to the same carbon…

Q: A mutation that changes an alanine to a leucine in the nucleus of a protein leads to a less active…

A: Introduction: Each organism's DNA sequence is unique. Its base-pairs sequence can change from time…

Q: Which amino acid pair constitutes the hydrophobic patch on sickle cell hemoglobin that results in…

A: Sickle cell disease is caused due to inversion of one base pair (A -> T). Due to which, the sixth…

Q: Why do we not indicate the side chains of the amino acids that form the peptide bond (see Figure…

A: Peptide bond forms when two amino acids react with each other through their alpha-amino and…

Q: Calculate the pl of the following Peptide

A: At extreme low pH, molecule is fully protonated as the pH increase more than pKa of an ionizable…

Q: Titrated the polypeptide with DTNB. The absorbance of the obtained yellow color was 0.16. 1.…

A: "Since you have asked multiple questions, we will solve the first two question for you. If you want…

Q: Reaction of the  α-carboxyl group of an amino acid or peptide with  phenylisothiocyanate allows for…

A: Above statement is about Edman degradation. It ia a method of DNA sequencing.

Q: you were given an unknown peptide. Explain in detail how you would determine the amino acid sequence…

A: The amino acids that form the protein are mostly L forms. The carboxyl group of amino acids in the…

Q: Which of the following sequences represents a recognition site for N-linked glycosylation where X is…

A: N-linked glycosylation, is the attachment of an oligosaccharide,  sometimes also referred to as…

Q: Heparin, a highly negatively charged glycosaminoglycan, is used clinically as an anticoagulant. It…

A: Heparin is an anticoagulant that prevents the formation of blood clots. It is used to treat and…

Q: The hormones oxytocin and vasopressin are 9-mer peptides than differ in the identity of only two…

A: Hormones are chemical messengers in our bodies. They are transported through the bloodstream. Their…

Q: How many different sequences of mRNA could encode a peptide with the sequence…

A: mRNA is decoded by the cells by reading their nucleotides in groups of three known as codons where…

Q: Given below are sequences of amino acids present in an oligo-peptide chain. Count the overall charge…

A: Oligo-peptide is the peptide chain formed by joining the amino acids with the help of peptide…

Q: "de 96 5 no

A: Answer :- The pH of the solution and the pKa values of the side chains of amino acids must be taken…

Q: Subjecting this peptide to one cycle of the Edman degradation would result in L-M-F-V-W-E-Q-A-P-S-P…

A: Edman degradation was developed by Pehr Edman. In Edmam degradation the amino acid sequence of a…

Q: Two melanocyte-stimulating hormones have the following amino acid sequences. Take a highlighter or…

A: Conserved sequences are the amino acid sequence that remain identical between two or more species…

Q: A number of fragments that will be formed by cleaving the peptide Met-Ala-Lys-Met-Arg-Phe-Met-An by…

A: Proteins are one of the macromolecules present in the body. They provide structural support,…

Q: A polypeptide is cleaved into peptides by treatment with trypsin and cyanogen bromide, and then the…

A: Trypsin cleaves specifically peptide bonds at the C-terminal side of lysine (K) and arginine (R)…

Q: A tetradecapeptide (14 amino acid residues) gives the following peptide fragments on partial…

A: A peptide is sequence of amino acids in which different amino acids are joined through peptide bond…

Q: a. Identify the type of mutation shown below. b. How many amino acids are affected? c. What type of…

A: A mutation is a change in a DNA sequence. It can result from DNA copying mistakes made during cell…

Q: You are in the process of determining theamino acid sequence of a peptide. After trypsin digestion…

A: An amino acid is an organic molecule that is made up of a basic amino group, an acidic carboxyl…

Q: pH @1 of Cys-His-Glu-Met-Ile-Ser-Thr-Arg-Tyr

A: Peptides are organic compounds made up of amino acids connected by peptide bonds. The specific…

Q: Which of the peptide sequences below best matches the hydropathy plot shown? 1. ILYYAGSREDHSGYLIL 2.…

A: Based on the hydropathy plot shown, which has regions of both positive and negative values…

Q: You are trying to determine the PTMs on your protein of interest, so you set up a mass spectrometry…

A: The modification of proteins after its biosynthesis is called post-translational modification (PTM).…

Q: Consider a hexapeptide of the sequence thr asn glu trp lys gln. A researcher decided that this…

A: The translation is the process of the formation of polypeptide chains of amino acids that lead to…

Q: Sickling occurs in deoxyhemoglobin S but not in oxyhemoglobin S. Oxyhemoglobin has a small,…

A: Sickling is the process where the haemoglobin protein inside the RBC cell clumps together this…