A new drug product is found to be ineffective after it has decomposed 30%. The original concentration of one sample was 5.0 mg/mL; when assayed 20 mos later, the concentration was found to be 4.2 mg/ml. Assuming that the decomposition is first-order, what should be the expiration time on the label ? How much of the active drug is lost at expiration if the label claim is 300 mg ?
A new drug product is found to be ineffective after it has decomposed 30%. The original concentration of one sample was 5.0 mg/mL; when assayed 20 mos later, the concentration was found to be 4.2 mg/ml. Assuming that the decomposition is first-order, what should be the expiration time on the label ? How much of the active drug is lost at expiration if the label claim is 300 mg ?
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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. A new drug product is found to be ineffective after it has decomposed 30%. The
original concentration of one sample was 5.0 mg/mL; when assayed 20 mos later,
the concentration was found to be 4.2 mg/ml. Assuming that the decomposition is
first-order, what should be the expiration time on the label ?
How much of the active drug is lost at expiration if the label claim is 300 mg ?
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