A new drug product is found to be ineffective after it has decomposed 30%. The original concentration of one sample was 5.0 mg/mL; when assayed 20 mos later, the concentration was found to be 4.2 mg/ml. Assuming that the decomposition is first-order, what should be the expiration time on the label ? How much of the active drug is lost at expiration if the label claim is 300 mg ?
A new drug product is found to be ineffective after it has decomposed 30%. The original concentration of one sample was 5.0 mg/mL; when assayed 20 mos later, the concentration was found to be 4.2 mg/ml. Assuming that the decomposition is first-order, what should be the expiration time on the label ? How much of the active drug is lost at expiration if the label claim is 300 mg ?
Chemistry & Chemical Reactivity
10th Edition
ISBN:9781337399074
Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel
Chapter14: Chemical Kinetics: The Rates Of Chemical Reactions
Section: Chapter Questions
Problem 17PS: The decomposition of SO2Cl2 is a first-order reaction: SO2Cl2(g) SO2(g) + Cl2(g) The rate constant...
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. A new drug product is found to be ineffective after it has decomposed 30%. The
original concentration of one sample was 5.0 mg/mL; when assayed 20 mos later,
the concentration was found to be 4.2 mg/ml. Assuming that the decomposition is
first-order, what should be the expiration time on the label ?
How much of the active drug is lost at expiration if the label claim is 300 mg ?
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