(a) NaBD4 CH3CH,OH (b) NABH4 CH3CH,OD

Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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### Reduction of Benzophenone: Experimental Setups

**Figure Description:**

The image displays two experimental setups for the reduction of benzophenone using a reducing agent. Benzophenone's structure is represented in both parts (a) and (b) of the image.

**(a)**

- **Chemical Structure:** The diagram shows benzophenone, which consists of two benzene rings (phenyl groups) attached to a central carbonyl (C=O) group.
- **Reaction Conditions:** 
  - **Reducing Agent:** Sodium borodeuteride (NaBD₄)
  - **Solvent:** Ethanol (CH₃CH₂OH)

**(b)**

- **Chemical Structure:** Identical to part (a), benzophenone with two benzene rings and a carbonyl group.
- **Reaction Conditions:**
  - **Reducing Agent:** Sodium borohydride (NaBH₄)
  - **Solvent:** Deuterated ethanol (CH₃CH₂OD)

### Explanation:

The image illustrates two variations in the standard reduction reaction of benzophenone, focusing on isotopic labeling:

- **Isotope Effect:** The use of NaBD₄ in part (a) introduces deuterium into the reduction process, which can be crucial for studying kinetic isotope effects in experiments.
- **Deuterated Solvent:** Similarly, using deuterated ethanol (CH₃CH₂OD) in part (b) can aid in tracing isotopic hydrogen incorporation into reaction products.

These diagrams are useful for understanding how isotopic labeling is applied in organic chemistry to study reaction mechanisms and pathways.
Transcribed Image Text:### Reduction of Benzophenone: Experimental Setups **Figure Description:** The image displays two experimental setups for the reduction of benzophenone using a reducing agent. Benzophenone's structure is represented in both parts (a) and (b) of the image. **(a)** - **Chemical Structure:** The diagram shows benzophenone, which consists of two benzene rings (phenyl groups) attached to a central carbonyl (C=O) group. - **Reaction Conditions:** - **Reducing Agent:** Sodium borodeuteride (NaBD₄) - **Solvent:** Ethanol (CH₃CH₂OH) **(b)** - **Chemical Structure:** Identical to part (a), benzophenone with two benzene rings and a carbonyl group. - **Reaction Conditions:** - **Reducing Agent:** Sodium borohydride (NaBH₄) - **Solvent:** Deuterated ethanol (CH₃CH₂OD) ### Explanation: The image illustrates two variations in the standard reduction reaction of benzophenone, focusing on isotopic labeling: - **Isotope Effect:** The use of NaBD₄ in part (a) introduces deuterium into the reduction process, which can be crucial for studying kinetic isotope effects in experiments. - **Deuterated Solvent:** Similarly, using deuterated ethanol (CH₃CH₂OD) in part (b) can aid in tracing isotopic hydrogen incorporation into reaction products. These diagrams are useful for understanding how isotopic labeling is applied in organic chemistry to study reaction mechanisms and pathways.
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