A local anesthetic (Na+ channel blocker) should do which of the following Make the resting membrane potential more negative Decrease the after hyperpolarization Block the rising phase of the AP None of these

A local anesthetic (Na+ channel blocker) should do which of the following Make the resting membrane potential more negative Decrease the after hyperpolarization Block the rising phase of the AP None of these

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section: Chapter Questions

Problem 1RE: Conformational changes in channel proteins brought about by voltage changes are responsible for...

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Concept explainers

Osmosis

In simple words, osmosis is the slow, gradual movement of a liquid through a membrane. But there are nuances to this process. For instance, there has to be an imbalance in the distribution of solute in the liquid on either side of the membrane, which has to be semipermeable. The liquid in the region with a lower solute concentration moves to the region with a higher concentration, thereby displacing the solution in the process. The objective is to equalize the concentration of molecules on both sides of the membrane; the displacement of liquid can be viewed as a byproduct of this equalization. Since there is no energy required to carry osmosis, it is considered a passive process.

Question

A local anesthetic (Na⁺ channel blocker) should do which of the following

		Make the resting membrane potential more negative
		Decrease the after hyperpolarization
		Block the rising phase of the AP
		None of these

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Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)
A membrane potential (Vm) labeled axis on the graph In the graph draw the phases of the action potential Include the channels involved and when they open and close matching them to the Vm Indicate the periods in which the action potential can or cannot occur
Table - Summary of the Events of an Action Potential Stage Name of stage Membrane Potential Movement of Na+ or Status of voltage-gated ion channels (mV) K+ in or out of the аxon 1 2 3 4 5
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This patient's hypokalemia was due to his profuse sweating the previous day and the subsequent loss of potassium ions at the kidneys. How would his hypokalemia affect action potential generation? O the cell membrane potential will become more positive and facilitate action potential generation O the cell membrane potential will become more negative and it will be more difficult to generate an action potential action potentials will be generated at a higher frequency O a and c
Based upon the changes in permeability seen in the trace below and your knowledge of ion distributions across a cell, predict how ion movements would change during an action potential. Drag and drop each phrase into the appropriate box on the action potential trace. Drag the appropriate labels to their respective targets. Note: not all labels will be used. ►View Available Hint(s) Sodium (Na+) ions move to the axon Sodium (Na) ions move out of the axon Less potassium (K) ions move out of the axon Potassium (K) ions move out of the axon Potassium (K¹) ions move into the axon Sodium (Na) ions stop moving in Membrane potential (mv) +30 +10 0 -10- -30 -50 -70 -90 A PNa 0 PNa 5 6 1 PK Threshold PK 2 Reset Help
Action potentials propagate in one direction because of: O K+ Voltage-gated Channels become inactive for a while O Nat Voltage-gated Channels become inactive for a while O K+ nongated Channels become inactive for a while O Nat nongated Channels become inactive for a while
Why do voltage-gated sodium channels have three states (open, closed, refractory/open-block)? Select all that apply. Select one or more answers and submit. For keyboard navigation... SHOW MORE ✓ a b с Multiple answers: Multiple answers are accepted for this question d To keep action potentials from going backwards To speed up the refractory period To prevent the channels from opening during repolarization To allow hyperpolarization to occur Answered Resubmit
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