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A large randomized trial was conducted to assess the efficacy of Chantix for smoking cessation compared with bupropion (more commonly known as Wellbutrin or Zyban) and a placebo. Chantix is different from most other quit-smoking products in that it targets nicotine receptors in the brain, attaches to them, and blocks nicotine from reaching them, while bupropion is an antidepressant often used to help people stop smoking. Generally healthy smokers who smoked at least 10 cigarettes per day were assigned at random to take Chantix (n = 352), bupropion (n = 329), or a placebo (n = 344). The response %3D measure is continuous cessation from smoking for Weeks 9 through 12 of the study. A two-way table of the results is given. Treatment Chantix Bupropion Placebo No smoking in Weeks 9–12 155 97 61 Smoked in Weeks 9–12 197 232 283

A large randomized trial was conducted to assess the efficacy of Chantix for smoking cessation compared with bupropion (more commonly known as Wellbutrin or Zyban) and a placebo. Chantix is different from most other quit-smoking products in that it targets nicotine receptors in the brain, attaches to them, and blocks nicotine from reaching them, while bupropion is an antidepressant often used to help people stop smoking. Generally healthy smokers who smoked at least 10 cigarettes per day were assigned at random to take Chantix (n = 352), bupropion (n = 329), or a placebo (n = 344). The response %3D measure is continuous cessation from smoking for Weeks 9 through 12 of the study. A two-way table of the results is given. Treatment Chantix Bupropion Placebo No smoking in Weeks 9–12 155 97 61 Smoked in Weeks 9–12 197 232 283

A First Course in Probability (10th Edition)
A First Course in Probability (10th Edition)
10th Edition
ISBN:9780134753119
Author:Sheldon Ross
Publisher:Sheldon Ross
Chapter1: Combinatorial Analysis
Section: Chapter Questions
Problem 1.1P: a. How many different 7-place license plates are possible if the first 2 places are for letters and...
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A large randomized trial was conducted to assess the efficacy of Chantix for smoking cessation compared with bupropion (more commonly known as Wellbutrin or Zyban) and a placebo. Chantix is different from most other quit-smoking products in that it targets nicotine receptors in the brain, attaches to them, and blocks nicotine from reaching them, while bupropion is an antidepressant often used to help people stop smoking. Generally healthy smokers who smoked at least 10 cigarettes per day were assigned at random to take Chantix (n = 352), bupropion (n = 329), or a placebo (n = 344). The response measure is continuous cessation from smoking for Weeks 9 through 12 of the study. A two-way table of the results is given. Treatment Chantix Bupropion Placebo No smoking in Weeks 9–12 155 97 61 Smoked in Weeks 9–12 197 232 283 To access the complete data set, click the link for your preferred software format: Excel Minitab JMP SPSS TI R Mac-TXT PC-TXT CSV CrunchIt! STATE: How does whether a subject smoked in Weeks 9-12 depend on the treatment received? PLAN: Select the best plan to investigate the question. From the given two-way table of results, find and compare the conditional distributions of treatment (Chantix, bupropion, and placebo) for each outcome (success, no success). From the given two-way table of results, find and compare the conditional distributions of outcome (success, no success) for each treatment (Chantix, bupropion, and placebo). From the given two-way table of results, find and compare the sample proportions of all six combinations of outcome (success, no success) and treatment (Chantix, bupropion, and placebo). Do a z test.
Transcribed Image Text:A large randomized trial was conducted to assess the efficacy of Chantix for smoking cessation compared with bupropion (more commonly known as Wellbutrin or Zyban) and a placebo. Chantix is different from most other quit-smoking products in that it targets nicotine receptors in the brain, attaches to them, and blocks nicotine from reaching them, while bupropion is an antidepressant often used to help people stop smoking. Generally healthy smokers who smoked at least 10 cigarettes per day were assigned at random to take Chantix (n = 352), bupropion (n = 329), or a placebo (n = 344). The response measure is continuous cessation from smoking for Weeks 9 through 12 of the study. A two-way table of the results is given. Treatment Chantix Bupropion Placebo No smoking in Weeks 9–12 155 97 61 Smoked in Weeks 9–12 197 232 283 To access the complete data set, click the link for your preferred software format: Excel Minitab JMP SPSS TI R Mac-TXT PC-TXT CSV CrunchIt! STATE: How does whether a subject smoked in Weeks 9-12 depend on the treatment received? PLAN: Select the best plan to investigate the question. From the given two-way table of results, find and compare the conditional distributions of treatment (Chantix, bupropion, and placebo) for each outcome (success, no success). From the given two-way table of results, find and compare the conditional distributions of outcome (success, no success) for each treatment (Chantix, bupropion, and placebo). From the given two-way table of results, find and compare the sample proportions of all six combinations of outcome (success, no success) and treatment (Chantix, bupropion, and placebo). Do a z test.
From the given two-way table of results, find and compare the sample proportions of all six combinations of outcome (success, no success) and treatment (Chantix, bupropion, and placebo). Do a z test. SOLVE: Calculate the percent of successes (no smoking in Weeks 9–12) for each treatment. (Enter your answers as percents rounded to one decimal place.) Chantix: % bupropion: % placebo: % CONCLUDE: How does whether a subject smoked in Weeks 9–12 depend on the treatment received? The bupropion group subjects were the least likely to have smoked in Weeks 9–12. O The placebo group subjects were the least likely to have smoked in Weeks 9–12. O There is no clear evidence of one treatment differing from another in this respect. O The Chantix group subjects were the least likely to have smoked in Weeks 9–12.
Transcribed Image Text:From the given two-way table of results, find and compare the sample proportions of all six combinations of outcome (success, no success) and treatment (Chantix, bupropion, and placebo). Do a z test. SOLVE: Calculate the percent of successes (no smoking in Weeks 9–12) for each treatment. (Enter your answers as percents rounded to one decimal place.) Chantix: % bupropion: % placebo: % CONCLUDE: How does whether a subject smoked in Weeks 9–12 depend on the treatment received? The bupropion group subjects were the least likely to have smoked in Weeks 9–12. O The placebo group subjects were the least likely to have smoked in Weeks 9–12. O There is no clear evidence of one treatment differing from another in this respect. O The Chantix group subjects were the least likely to have smoked in Weeks 9–12.
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