A good Williamson synthesis of ethyl methyl ether would beCH3CH2¬O- Na+ + CH3I ¡ CH3CH2¬O¬CH3 + NaIsodium ethoxide methyl iodide ethyl methyl etherWhat is wrong with the following proposed synthesis of ethyl methyl ether? First, ethanolis treated with acid to protonate the hydroxy group (making it a good leaving group), andthen sodium methoxide is added to displace water.CH3CH2(incorrect synthesis of ethyl methyl ether)OH + H+ CH3CH2 OH2+CH3CH2 O CH3

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A good Williamson synthesis of ethyl methyl ether would be
CH3CH2¬O- Na+ + CH3I ¡ CH3CH2¬O¬CH3 + NaI
sodium ethoxide methyl iodide ethyl methyl ether
What is wrong with the following proposed synthesis of ethyl methyl ether? First, ethanol
is treated with acid to protonate the hydroxy group (making it a good leaving group), and
then sodium methoxide is added to displace water.
CH3CH2
(incorrect synthesis of ethyl methyl ether)
OH + H+ CH3CH2 OH2
+
CH3CH2 O CH3

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