A) Give the mechanism of Wolff-Kishner reduction on 1-phenylpropan-1-one. What isHuang-Minlon modification of the reaction?B) Predict the products you expect when the following starting material undergoesoxidation with an excess of each of the reagents shown below.HỌD)1)C) Give the general mechanism of metal hydride reduction. Illustrate the chemoselectivity of NaBH4 with two examples?ii)iii)iv)-CH₂OH(i) Chromic acid(ii) PCC (pyridinium chlorochromate)(iii) DMSO and oxalyl chloride(iv) DMP (periodinane) reagentCOOHCH₂OHComplete the following reactions.B₂H/THFOEtK-Selectride /THF-78°CNa, EtOHNH₂1) 0₂ii) (CH₂)₂SPage 314

Answered: A) Give the mechanism of Wolff-Kishner…

A) Give the mechanism of Wolff-Kishner reduction on 1-phenylpropan-1-one. What is Huang-Minlon modification of the reaction?

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question

A) Give the mechanism of Wolff-Kishner reduction on 1-phenylpropan-1-one. What is
Huang-Minlon modification of the reaction?
B) Predict the products you expect when the following starting material undergoes
oxidation with an excess of each of the reagents shown below.
HỌ
D)
1)
C) Give the general mechanism of metal hydride reduction. Illustrate the chemo
selectivity of NaBH4 with two examples?
ii)
iii)
iv)
-CH₂
OH
(i) Chromic acid
(ii) PCC (pyridinium chlorochromate)
(iii) DMSO and oxalyl chloride
(iv) DMP (periodinane) reagent
COOH
CH₂OH
Complete the following reactions.
B₂H/THF
OEt
K-Selectride /THF
-78°C
Na, EtOH
NH₂
1) 0₂
ii) (CH₂)₂S
Page 314

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