A dose of 300 mg was administered to healthy volunteer. Five blood samples were collectedat 0, 2, 4, 6, 8 hours. Plasma was separated from each blood sample and analyzed for drugconcentration. The collected data are shown in the table below. Determine the total AUC(mg.hr/L)Time (hr) Cp (mg/L) A(AUC mg.hr/L) AUC mg.hr/L02468DOAAUC₁-2=AAUC last-00kel==(CP, +CP2)x(t - t)2CPlastkel43.12.62.32.1In(CPfrom left on line) - In(CPfrom right on line)from right on line from left on linea) 110.67 mg.hr/Lb) 68.8 mg.hr/Lc) 10.34 mg.hr/Ld) 7.86 mg.hr/LHide question 5 feedbackkel = 0.045

AUC - Area under the curve.Through this we can calculate the total amount of drug absorbed into…

Answered: A dose of 300 mg was administered to…

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

Problem 1SRQ

See similar textbooks

Similar questions

The erythrocyte sedimentation rate (heaviness) test of a blood sample is often used as a diagnosis of immune disorders and some other diseases. Assuming that the red blood cells are about a sphere with a diameter of (approximately 5 um) and a density (g/ml 1.125), and the density and viscosity of the plasma in which the red blood cells are settled (Pa.s), (1025 kg/m3 10-3 x 1.5) On arrangement and acceleration m/s2 9.81 Calculate the erythrocyte sedimentation rate (settlement rate).
1. What volume of potassium phosphate will you add? 2. What will the infustion rate in mL/hr? 3. How many total mEq of K+ will the patient recieve?
A patient is taking acetaminophen (Tylenol) 325 mg, 2 tablets PO every 6 hours (4 doses in 24hrs). How manygrams is the patient receiving in 24 hours? Maximun safe dose of acetaminophen is 3000mg/24hrs. Is this safe? O 1300mg/24hrs. No O 1300mg/24hrs. Yes O 2600mg/24 hr. No O 2600mg/24hrs. Yes
You need to give aciclovir as an infusion at a dose of 5 mg/kg every 8 hours. The patient weighs 76 kg and aciclovir is available as 250 mg vials. How many vials do you need for each dose?
When determining CFUs for a dilution of the same sample at 10-2 and 10-3 which of the following results would seem the most accurate to you? Explain why in the space below. A. 110,000 CFU/mL for 10-2; and 140,000 CFU/mL 10-3 B. 110,000 CFU/mL for 10-2; and 14,000 CFU/mL 10-3 C. 10,000 CFU/mL for 10-2; and 140,000 CFU/mL 10-3 D. none of the above
The regimen for a drug is as follows: 5mcg/kg q week x 2, then 7mcg/kg q 2 weeks. Calculate the dose in mcg that a 143 lbs. patient receives in a month.
Medication with strength 125 mg/mL has been ordered at 10 mg/kg. The patient weighs 243 lb. How much should be administered? (If less than 1, round to the nearest hundredth; otherwise, round to the nearest tenth.)
a 4 YO 38lb child with hypertension has to be ordered furosemide 1mg/kg/dose PO twice daily. Furosemide oral solution is available in 60mL bottles containing 10mg/mL. How many mL will you administer each dose?
An IV infusion is to contain 40 mEq of potassium ion and 10 mEq of sodium ion in 500 mL of D5W.Using a 20% w/v potassium chloride injection (MW 74.5, valence of 1) and 0.45% sodium chlorideinjection (MW 58.5, valence of 1), how many milliliters of each should be added to the 500mL bag ofD5W to supply the required ions?
A prescription order calls for procainamide 0.5 g. In the pharmacy, the technician uses a 1g/10 mL vial to prepare the dose, which is injected into a 150 mL D5W IV bag for infusion. Assuming conventional overfill for the IV bag, what should the flow rate be in mL/hr if the dose of the drug is 2 mg/min? Round to the nearest whole mL.
1gtt OU q4h x 72h then q6h x 10 days # 10 mL. The physician then tells the patient to continue the last dose until the bottle is empty. How many days will the medication last (what is the Estimated Days Supply)? this isnt 23.7 nor 24 nor 4 days
A options are: 50 mL,75 mL,100 mL, 125 mL, 150 mL or none of the above C options are: 0.25J, 0.75J, 1.25J, 1.75J or none of the above D options are: green PV loop, gray PV loop, red PV loop or none of the above

SEE MORE QUESTIONS

Recommended textbooks for you

Phlebotomy Essentials

Nursing

ISBN:

9781451194524

Author:

Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:

JONES+BARTLETT PUBLISHERS, INC.

Gould's Pathophysiology for the Health Profession…

Nursing

ISBN:

9780323414425

Author:

Robert J Hubert BS

Publisher:

Saunders

Fundamentals Of Nursing

Nursing

ISBN:

9781496362179

Author:

Taylor, Carol (carol R.), LYNN, Pamela (pamela Barbara), Bartlett, Jennifer L.

Publisher:

Wolters Kluwer,

Phlebotomy Essentials

Nursing

ISBN:

9781451194524

Author:

Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:

JONES+BARTLETT PUBLISHERS, INC.

Gould's Pathophysiology for the Health Profession…

Nursing

ISBN:

9780323414425

Author:

Robert J Hubert BS

Publisher:

Saunders

Fundamentals Of Nursing

Nursing

ISBN:

9781496362179

Author:

Taylor, Carol (carol R.), LYNN, Pamela (pamela Barbara), Bartlett, Jennifer L.

Publisher:

Wolters Kluwer,

Fundamentals of Nursing, 9e

Nursing

ISBN:

9780323327404

Author:

Patricia A. Potter RN MSN PhD FAAN, Anne Griffin Perry RN EdD FAAN, Patricia Stockert RN BSN MS PhD, Amy Hall RN BSN MS PhD CNE

Publisher:

Elsevier Science

Study Guide for Gould's Pathophysiology for the H…

Nursing

ISBN:

9780323414142

Author:

Hubert BS, Robert J; VanMeter PhD, Karin C.

Publisher:

Saunders

Issues and Ethics in the Helping Professions (Min…

Nursing

ISBN:

9781337406291

Author:

Gerald Corey, Marianne Schneider Corey, Cindy Corey

Publisher:

Cengage Learning

SEE MORE TEXTBOOKS